FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3033572034> ?p ?o ?g. }

• W3033572034 endingPage "196" @default.
• W3033572034 startingPage "190" @default.
• W3033572034 abstract "BackgroundDiscriminating active tuberculosis (ATB) from latent tuberculosis infection (LTBI) remains challenging. This study aimed to investigate a diagnostic model based on a combination of iron metabolism and the TB-specific antigen/phytohemagglutinin ratio (TBAg/PHA ratio) in T-SPOT.TB assay for differentiation between ATB and LTBI.MethodsA total of 345 participants with ATB (n = 191) and LTBI (n = 154) were recruited based on positive T-SPOT.TB results at Tongji hospital between January 2017 and January 2020. Iron metabolism analysis was performed simultaneously. A diagnostic model for distinguishing ATB from LTBI was established according to multivariate logistic regression.ResultsThe TBAg/PHA ratio showed 64.00% sensitivity and 90.10% specificity in distinguishing ATB from LTBI when a threshold of 0.22 was used. All iron metabolism biomarkers in the ATB group were significantly different from those in the LTBI group. Specifically, serum ferritin and soluble transferrin receptor in ATB were significantly higher than LTBI. On the contrary, serum iron, transferrin, total iron binding capacity, and unsaturated iron binding capacity in ATB were significantly lower than LTBI. The combination of iron metabolism indicators accurately predicted 60.00% of ATB cases and 91.09% of LTBI subjects, respectively. Moreover, the combination of iron metabolism indexes and TBAg/PHA ratio resulted in a sensitivity of 88.80% and specificity of 90.10%. Furthermore, the performance of models established in the Qiaokou cohort was confirmed in the Caidian cohort.ConclusionsThe data suggest that the combination of iron metabolism indexes and TBAg/PHA ratio could serve as a biomarker to distinguish ATB from LTBI in T-SPOT-positive individuals." @default.
• W3033572034 created "2020-06-12" @default.
• W3033572034 creator A5003476767 @default.
• W3033572034 creator A5009451090 @default.
• W3033572034 creator A5045477206 @default.
• W3033572034 creator A5045669644 @default.
• W3033572034 creator A5048369268 @default.
• W3033572034 creator A5049806666 @default.
• W3033572034 creator A5066533723 @default.
• W3033572034 creator A5069526766 @default.
• W3033572034 creator A5075012844 @default.
• W3033572034 date "2020-08-01" @default.
• W3033572034 modified "2023-10-14" @default.
• W3033572034 title "A combination of iron metabolism indexes and tuberculosis-specific antigen/phytohemagglutinin ratio for distinguishing active tuberculosis from latent tuberculosis infection" @default.
• W3033572034 cites W1576551594 @default.
• W3033572034 cites W2040982827 @default.
• W3033572034 cites W2063804160 @default.
• W3033572034 cites W2064736441 @default.
• W3033572034 cites W2082339691 @default.
• W3033572034 cites W2115048609 @default.
• W3033572034 cites W2120091037 @default.
• W3033572034 cites W2165805436 @default.
• W3033572034 cites W2234961310 @default.
• W3033572034 cites W2342033899 @default.
• W3033572034 cites W2345756873 @default.
• W3033572034 cites W2514999355 @default.
• W3033572034 cites W2516589719 @default.
• W3033572034 cites W2604229370 @default.
• W3033572034 cites W2605056209 @default.
• W3033572034 cites W2612195143 @default.
• W3033572034 cites W2735080693 @default.
• W3033572034 cites W2754779587 @default.
• W3033572034 cites W2767182248 @default.
• W3033572034 cites W2792213513 @default.
• W3033572034 cites W2795503272 @default.
• W3033572034 cites W2796838788 @default.
• W3033572034 cites W2801623506 @default.
• W3033572034 cites W2810160615 @default.
• W3033572034 cites W2897480194 @default.
• W3033572034 cites W2899736836 @default.
• W3033572034 cites W2902094775 @default.
• W3033572034 cites W2916659402 @default.
• W3033572034 cites W2916881134 @default.
• W3033572034 cites W2942068613 @default.
• W3033572034 cites W2942233746 @default.
• W3033572034 cites W2943251522 @default.
• W3033572034 cites W2950875755 @default.
• W3033572034 cites W2979952761 @default.
• W3033572034 cites W3011382870 @default.
• W3033572034 cites W3012815004 @default.
• W3033572034 cites W3016847598 @default.
• W3033572034 cites W4211088350 @default.
• W3033572034 cites W4211157605 @default.
• W3033572034 doi "https://doi.org/10.1016/j.ijid.2020.05.109" @default.
• W3033572034 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32497795" @default.
• W3033572034 hasPublicationYear "2020" @default.
• W3033572034 type Work @default.
• W3033572034 sameAs 3033572034 @default.
• W3033572034 citedByCount "14" @default.
• W3033572034 countsByYear W30335720342020 @default.
• W3033572034 countsByYear W30335720342021 @default.
• W3033572034 countsByYear W30335720342022 @default.
• W3033572034 countsByYear W30335720342023 @default.
• W3033572034 crossrefType "journal-article" @default.
• W3033572034 hasAuthorship W3033572034A5003476767 @default.
• W3033572034 hasAuthorship W3033572034A5009451090 @default.
• W3033572034 hasAuthorship W3033572034A5045477206 @default.
• W3033572034 hasAuthorship W3033572034A5045669644 @default.
• W3033572034 hasAuthorship W3033572034A5048369268 @default.
• W3033572034 hasAuthorship W3033572034A5049806666 @default.
• W3033572034 hasAuthorship W3033572034A5066533723 @default.
• W3033572034 hasAuthorship W3033572034A5069526766 @default.
• W3033572034 hasAuthorship W3033572034A5075012844 @default.
• W3033572034 hasBestOaLocation W30335720341 @default.
• W3033572034 hasConcept C126322002 @default.
• W3033572034 hasConcept C142724271 @default.
• W3033572034 hasConcept C144494922 @default.
• W3033572034 hasConcept C203014093 @default.
• W3033572034 hasConcept C22814914 @default.
• W3033572034 hasConcept C2776244011 @default.
• W3033572034 hasConcept C2777975735 @default.
• W3033572034 hasConcept C2778319317 @default.
• W3033572034 hasConcept C2778917026 @default.
• W3033572034 hasConcept C2779806340 @default.
• W3033572034 hasConcept C2779875672 @default.
• W3033572034 hasConcept C2781069245 @default.
• W3033572034 hasConcept C3019184707 @default.
• W3033572034 hasConcept C58471807 @default.
• W3033572034 hasConcept C71924100 @default.
• W3033572034 hasConcept C72563966 @default.
• W3033572034 hasConceptScore W3033572034C126322002 @default.
• W3033572034 hasConceptScore W3033572034C142724271 @default.
• W3033572034 hasConceptScore W3033572034C144494922 @default.
• W3033572034 hasConceptScore W3033572034C203014093 @default.
• W3033572034 hasConceptScore W3033572034C22814914 @default.
• W3033572034 hasConceptScore W3033572034C2776244011 @default.
• W3033572034 hasConceptScore W3033572034C2777975735 @default.
• W3033572034 hasConceptScore W3033572034C2778319317 @default.

• next