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- W3033591946 abstract "Immunoglobulin E (IgE)–mediated food allergy (FA) is the leading cause of anaphylaxis in children, although fatal reactions remain rare. 1 Michelson K.A. Dribin T.E. Vyles D. Neuman M.I. Trends in emergency care for anaphylaxis. J Allergy Clin Immunol Pract. 2020; 8: 767-768.e2 Abstract Full Text Full Text PDF PubMed Scopus (13) Google Scholar , 2 Turner P.J. Jerschow E. Umasunthar T. Lin R. Campbell D.E. Boyle R.J. Fatal anaphylaxis: mortality rate and risk factors. J Allergy Clin Immunol Pract. 2017; 5: 1169-1178 Abstract Full Text Full Text PDF PubMed Scopus (189) Google Scholar , 3 Dorris S. Fatal food anaphylaxis: registering a rare outcome. Ann Allergy Asthma Immunol. 2020; 124: 445-446 Abstract Full Text Full Text PDF PubMed Scopus (11) Google Scholar Strict adherence to avoidance diets and use of FA emergency management plans can considerably decrease reaction rates, with 1 study reporting a 60-fold reduced frequency of severe FA reactions. 4 Ewan P.W. Clark A.T. Efficacy of a management plan based on severity assessment in longitudinal and case-controlled studies of 747 children with nut allergy: proposal for good practice. Clin Exp Allergy. 2005; 35: 751-756 Crossref PubMed Scopus (102) Google Scholar However, which patients experience severe vs mild symptoms, as well as contributory factors, remains an area of active study. 5 Dribin T.E. Michelson K.A. Zhang Y. Schnadower D. Neuman M.I. Are children with a history of asthma more likely to have severe anaphylactic reactions? A retrospective cohort study. J Pediatr. 2020; 220: 159-164.e2 Abstract Full Text Full Text PDF PubMed Scopus (5) Google Scholar ,6 Turner P.J. Baumert J.L. Beyer K. et al. Can we identify patients at risk of life-threatening allergic reactions to food?. Allergy. 2016; 71: 1241-1255 Crossref PubMed Scopus (118) Google Scholar Currently, no unified definition of a severe FA reaction exists, calling into question which symptom or compilation of symptoms during a reaction constitute a severe label." @default.
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- W3033591946 date "2020-09-01" @default.
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- W3033591946 title "What constitutes a severe food allergy reaction?" @default.
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