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- W3033598052 abstract "There are few recent data about the prevalence of upper gastrointestinal subepithelial tumors (GI SETs). 0.76-1.7% of endoscopic prevalence of single center study has been reported. We reviewed medical and endoscopic reports of 55,306 subjects who underwent screening endoscopy at 8 university hospitals in Korea during 1 year from January to December 2015 and clinically followed. 1,062 SETs in 1,044 subjects (55.1 ± 11.2 years, male 53.6%) were diagnosed in 55,306 screening population enrolled (endoscopic prevalence, 1.99%). There is interorgan variability about prevalence (range, 1.23-4.06%). 285 of 1,044 subjects underwent EUS. Pathological diagnosis was done in 61 lesions. Clinical diagnosis using EUS imaging and follow up more than 1 year or pathological diagnosis was done in 295 lesions. The prevalence of upper GI SETs increased with age and was higher in male (57.6%). The most common location was stomach (n=681, 64.1%). The mean size was 13.2 ± 7.0 mm, mostly located in the 4th layer (65.5%) and 3rd layer (26.7%). In the 44 upper GI SET ≥ 2 cm in size, 8 lesions (18.2%) was the malignant or premalignant lesions (adenocarcinoma, n=1; GIST, n=7). Among 28 stomach SETs were ≥ 2 cm, 18 SETs (64%) were followed up without pathologic diagnosis, 16 of 18 SETs did not increase in size during median 46 months (range, 8-61), and other two resected lesions were proved to be leiomyomas. Five of twelve stomach SETs which were tried for pathologic confirmation were adenocarcinoma (n=1) and GIST (n=4). Twenty-nine of 130 duodenal SETs were tried to get pathology; however, pathologic diagnosis was obtained in only in 15 (52%). 1.5% (2 of 130) of all duodenal SETs was neuroendocrine tumor. The overall prevalence of upper GI SETs was 1.99% in Korea. 18% of upper GI SETs ≥ 2 cm was premalignant or malignant lesion and most of them were followed up depending on EUS imaging and clinical decision. But those lesions were remained unchanged. If the stomach lesions were tried for pathologic diagnosis first, about half of these lesions were proved to be premalignant or malignant. 1.5% duodenal SETs were neuroendocrine tumor." @default.
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- W3033598052 date "2020-06-01" @default.
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- W3033598052 title "Su1302 THE PREVALENCE, NATURAL COURSE, AND CLINICAL PRACTICE OF UPPER GASTROINTESTINAL SUBEPITHELIAL TUMORS IN KOREA" @default.
- W3033598052 doi "https://doi.org/10.1016/j.gie.2020.03.2148" @default.
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