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- W3033598833 abstract "Structural and biophysical studies show that CRM1(E571K) binds differently to a small subset of nuclear export signals (NESs). NESs of Mek1, RPS2, and 4E-T bind CRM1(E571K) >10-fold differently, but only 4E-T NES is accessible in the full-length protein. 4E-T is mislocalized to the nucleus in HEK 293 and patient cells carrying CRM1(E571K)." @default.
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- W3033598833 date "2020-08-01" @default.
- W3033598833 modified "2023-10-02" @default.
- W3033598833 title "Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation" @default.
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- W3033598833 doi "https://doi.org/10.1091/mbc.e20-04-0233" @default.
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