FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3033736710> ?p ?o ?g. }

• W3033736710 endingPage "108063" @default.
• W3033736710 startingPage "108063" @default.
• W3033736710 abstract "Previous studies found enlarged striatum and white matter in those with stimulants use disorders. Whether primarily ketamine users (Primarily-K) and ketamine users who co-used stimulants and other substances (K+PolyS) have abnormal brain volumes is unknown. This study aims to evaluate possible brain structural abnormalities, cognitive function and depressive symptoms, between Primarily-K and K+PolyS users. Striatal and white matter volumes were automatically segmented in 39 Primarily-K users, 41 K+PolyS users and 46 non-drug users (ND). Cognitive performance in 7 neurocognitive domains and depressive symptoms were also evaluated. Ketamine users had larger caudates than ND-controls (Right: 1-way-ANCOVA-p=0.035; K+PolyS vs. ND, p=0.030; Linear trend for K+PolyS>Primarily-K>ND, p=0.011; Left: 1-way-ANCOVA-p=0.047, Primarily-K vs. ND p=0.051) and larger total white matter (1-way ANCOVA-p=0.009, Poly+K vs. Primarily-K, p=0.05; Poly+K vs. ND p=0.011; Linear trend for K+PolyS>Primarily-K >ND, p=0.004). Across all ketamine users, they performed poorer on Arithmetic, learning and memory tasks, and were more depressed than Non-users (p<0.001 to p=0.001). Greater lifetime ketamine usage correlated with more depressive symptoms (r=0.27, p=0.008). Larger white matter correlated with better learning across all participants (r=0.21, p=0.019), while larger right caudate correlated with lower depression scores in ketamine users (r=-0.28, p=0.013). Ketamine users had larger caudates and total white matter than ND-controls. The even larger white matter in K+PolyS users suggests additive effects from co-use of ketamine and stimulants. However, across the ketamine users, since greater volumes were associated with better learning and less depressive symptom, the enlarged caudates and white matter might represent a compensatory response." @default.
• W3033736710 created "2020-06-12" @default.
• W3033736710 creator A5007992227 @default.
• W3033736710 creator A5048441451 @default.
• W3033736710 creator A5061484061 @default.
• W3033736710 creator A5063514061 @default.
• W3033736710 creator A5064857868 @default.
• W3033736710 creator A5079097887 @default.
• W3033736710 date "2020-08-01" @default.
• W3033736710 modified "2023-09-27" @default.
• W3033736710 title "Striatal and white matter volumes in chronic ketamine users with or without recent regular stimulant use" @default.
• W3033736710 cites W1566415063 @default.
• W3033736710 cites W1605670916 @default.
• W3033736710 cites W1944157238 @default.
• W3033736710 cites W1957682507 @default.
• W3033736710 cites W1961364466 @default.
• W3033736710 cites W1975599414 @default.
• W3033736710 cites W1987285132 @default.
• W3033736710 cites W1991310302 @default.
• W3033736710 cites W1991391691 @default.
• W3033736710 cites W1992861430 @default.
• W3033736710 cites W1996419739 @default.
• W3033736710 cites W1998023735 @default.
• W3033736710 cites W1999585620 @default.
• W3033736710 cites W2001078642 @default.
• W3033736710 cites W2001832353 @default.
• W3033736710 cites W2018820143 @default.
• W3033736710 cites W2024374498 @default.
• W3033736710 cites W2028561774 @default.
• W3033736710 cites W2030689820 @default.
• W3033736710 cites W2032267642 @default.
• W3033736710 cites W2034586698 @default.
• W3033736710 cites W2043626321 @default.
• W3033736710 cites W2043922939 @default.
• W3033736710 cites W2047276596 @default.
• W3033736710 cites W2050658578 @default.
• W3033736710 cites W2051045914 @default.
• W3033736710 cites W2051945849 @default.
• W3033736710 cites W2055993736 @default.
• W3033736710 cites W2057497430 @default.
• W3033736710 cites W2058046532 @default.
• W3033736710 cites W2060028107 @default.
• W3033736710 cites W2067456882 @default.
• W3033736710 cites W2069186876 @default.
• W3033736710 cites W2069546180 @default.
• W3033736710 cites W2070747002 @default.
• W3033736710 cites W2071881327 @default.
• W3033736710 cites W2072599915 @default.
• W3033736710 cites W2073139532 @default.
• W3033736710 cites W2074510414 @default.
• W3033736710 cites W2079852449 @default.
• W3033736710 cites W2084511194 @default.
• W3033736710 cites W2086505246 @default.
• W3033736710 cites W2089823571 @default.
• W3033736710 cites W2092802479 @default.
• W3033736710 cites W2098139332 @default.
• W3033736710 cites W2112015708 @default.
• W3033736710 cites W2117792476 @default.
• W3033736710 cites W2118335987 @default.
• W3033736710 cites W2120357670 @default.
• W3033736710 cites W2123778240 @default.
• W3033736710 cites W2129319557 @default.
• W3033736710 cites W2138001941 @default.
• W3033736710 cites W2147421654 @default.
• W3033736710 cites W2149466217 @default.
• W3033736710 cites W2150447827 @default.
• W3033736710 cites W2150914643 @default.
• W3033736710 cites W2154597590 @default.
• W3033736710 cites W2160829173 @default.
• W3033736710 cites W2193480309 @default.
• W3033736710 cites W2196711084 @default.
• W3033736710 cites W2205378079 @default.
• W3033736710 cites W2208088507 @default.
• W3033736710 cites W2232935910 @default.
• W3033736710 cites W2274655672 @default.
• W3033736710 cites W2301532486 @default.
• W3033736710 cites W2327160615 @default.
• W3033736710 cites W2339807712 @default.
• W3033736710 cites W2343932452 @default.
• W3033736710 cites W2411894862 @default.
• W3033736710 cites W2412496260 @default.
• W3033736710 cites W2468480849 @default.
• W3033736710 cites W2517085860 @default.
• W3033736710 cites W2528813378 @default.
• W3033736710 cites W2535240874 @default.
• W3033736710 cites W2589105429 @default.
• W3033736710 cites W2597426509 @default.
• W3033736710 cites W2622274120 @default.
• W3033736710 cites W2753332410 @default.
• W3033736710 cites W2762750184 @default.
• W3033736710 cites W2768009339 @default.
• W3033736710 cites W2768166779 @default.
• W3033736710 cites W2793350897 @default.
• W3033736710 cites W2794222335 @default.
• W3033736710 cites W2800657613 @default.
• W3033736710 cites W2800749866 @default.
• W3033736710 cites W2811304329 @default.
• W3033736710 cites W2887591832 @default.

• next