FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3033766051> ?p ?o ?g. }

• W3033766051 endingPage "AB260" @default.
• W3033766051 startingPage "AB260" @default.
• W3033766051 abstract "Full-thickness resection device (FTRD) utilizes an over-the-scope distal attachment device designed to perform endoscopic full-thickness resections (EFTRs) within the gastrointestinal (GI) tract. FTRD is increasingly used for the removal of lesions not amenable to traditional endoscopic techniques. Initial studies have shown promising but variable results. We conducted a systematic review and meta-analysis to evaluate the safety and efficacy of FTRD for EFTRs in the GI tract. Bibliographical databases (PubMed, Ovid, Scopus, EMBASE, Web of Science, Cochrane and Google scholar) were systematically searched to identify studies using FTRD for EFTR in the GI tract. In addition, abstracts published at major gastroenterology conferences within the last two years were also searched. Studies with < 10 patients and overlapping patients were excluded. The primary outcomes were the rate of technical success and histologically confirmed complete resection (R0). The secondary outcome was rate of adverse events. The pooled estimates with 95% confidence interval were computed using the random-effects model. I-square (I2) statistic was used to quantify heterogeneity. Fifteen studies with a total of 1752 patients were included in the final analysis. There were six prospective studies, eight retrospective studies, and one mixed study. The mean age ranged from 59.7 to 70 years, and 60% of patients were male. The most common indications for EFTR were recurrence or incomplete resection after prior polypectomy (50.7%), followed by primary non-lifting adenoma (17.8%), known intramucosal cancer (9.9%), submucosal lesions (9.2%) and lesions involving appendicular orifice (6.6%). The overall pooled technical success rate was 88.3% (95% CI: 0.86-0.89, I2=0%) and the most common reason reported for technical failure was snare malfunction or clip mis-deployment in 7.1% of cases. Overall pooled R0 resection rate was 78.9% [Figure 1] (95% CI: 0.75-0.82, I2=36.2%). The pooled incidence of the adverse event rate was 12.3% [Figure 2] (95% CI: 0.09-0.15, I2=32.6%). Most adverse events were minor; however, 1.9% patients required surgery for management of procedure-related complications such as perforation, stenosis, and appendicitis. FTRD appears to be an effective and overall safe modality for endoscopic full-thickness resection for lesions not amenable to traditional endoscopic resection techniques sparing formal surgical resection. Future studies regarding learning curve and cost-effectiveness analysis may aid in further adoption of EFTR in the GI tract.Figure 2Forest plot of adverse event ratesView Large Image Figure ViewerDownload Hi-res image Download (PPT)" @default.
• W3033766051 created "2020-06-12" @default.
• W3033766051 creator A5005641244 @default.
• W3033766051 creator A5010857889 @default.
• W3033766051 creator A5018064615 @default.
• W3033766051 creator A5032323138 @default.
• W3033766051 creator A5036469612 @default.
• W3033766051 creator A5038543156 @default.
• W3033766051 creator A5039431102 @default.
• W3033766051 creator A5065527380 @default.
• W3033766051 creator A5067762508 @default.
• W3033766051 creator A5088236048 @default.
• W3033766051 date "2020-06-01" @default.
• W3033766051 modified "2023-09-26" @default.
• W3033766051 title "Sa2052 SAFETY AND EFFICACY OF ENDOSCOPIC FULL-THICKNESS RESECTION DEVICE (FTRD) IN THE GASTROINTESTINAL TRACT: A SYSTEMATIC REVIEW AND META-ANALYSIS" @default.
• W3033766051 doi "https://doi.org/10.1016/j.gie.2020.03.1848" @default.
• W3033766051 hasPublicationYear "2020" @default.
• W3033766051 type Work @default.
• W3033766051 sameAs 3033766051 @default.
• W3033766051 citedByCount "0" @default.
• W3033766051 crossrefType "journal-article" @default.
• W3033766051 hasAuthorship W3033766051A5005641244 @default.
• W3033766051 hasAuthorship W3033766051A5010857889 @default.
• W3033766051 hasAuthorship W3033766051A5018064615 @default.
• W3033766051 hasAuthorship W3033766051A5032323138 @default.
• W3033766051 hasAuthorship W3033766051A5036469612 @default.
• W3033766051 hasAuthorship W3033766051A5038543156 @default.
• W3033766051 hasAuthorship W3033766051A5039431102 @default.
• W3033766051 hasAuthorship W3033766051A5065527380 @default.
• W3033766051 hasAuthorship W3033766051A5067762508 @default.
• W3033766051 hasAuthorship W3033766051A5088236048 @default.
• W3033766051 hasBestOaLocation W30337660511 @default.
• W3033766051 hasConcept C121608353 @default.
• W3033766051 hasConcept C126322002 @default.
• W3033766051 hasConcept C141071460 @default.
• W3033766051 hasConcept C159110652 @default.
• W3033766051 hasConcept C197934379 @default.
• W3033766051 hasConcept C2776478404 @default.
• W3033766051 hasConcept C2778435480 @default.
• W3033766051 hasConcept C2778866283 @default.
• W3033766051 hasConcept C2780581329 @default.
• W3033766051 hasConcept C44249647 @default.
• W3033766051 hasConcept C526805850 @default.
• W3033766051 hasConcept C61434518 @default.
• W3033766051 hasConcept C71924100 @default.
• W3033766051 hasConcept C95190672 @default.
• W3033766051 hasConceptScore W3033766051C121608353 @default.
• W3033766051 hasConceptScore W3033766051C126322002 @default.
• W3033766051 hasConceptScore W3033766051C141071460 @default.
• W3033766051 hasConceptScore W3033766051C159110652 @default.
• W3033766051 hasConceptScore W3033766051C197934379 @default.
• W3033766051 hasConceptScore W3033766051C2776478404 @default.
• W3033766051 hasConceptScore W3033766051C2778435480 @default.
• W3033766051 hasConceptScore W3033766051C2778866283 @default.
• W3033766051 hasConceptScore W3033766051C2780581329 @default.
• W3033766051 hasConceptScore W3033766051C44249647 @default.
• W3033766051 hasConceptScore W3033766051C526805850 @default.
• W3033766051 hasConceptScore W3033766051C61434518 @default.
• W3033766051 hasConceptScore W3033766051C71924100 @default.
• W3033766051 hasConceptScore W3033766051C95190672 @default.
• W3033766051 hasIssue "6" @default.
• W3033766051 hasLocation W30337660511 @default.
• W3033766051 hasOpenAccess W3033766051 @default.
• W3033766051 hasPrimaryLocation W30337660511 @default.
• W3033766051 hasRelatedWork W2034277954 @default.
• W3033766051 hasRelatedWork W2050106328 @default.
• W3033766051 hasRelatedWork W2409281747 @default.
• W3033766051 hasRelatedWork W2901780503 @default.
• W3033766051 hasRelatedWork W3106934121 @default.
• W3033766051 hasRelatedWork W3134635266 @default.
• W3033766051 hasRelatedWork W3159849630 @default.
• W3033766051 hasRelatedWork W4224217175 @default.
• W3033766051 hasRelatedWork W4292365292 @default.
• W3033766051 hasRelatedWork W4313554938 @default.
• W3033766051 hasVolume "91" @default.
• W3033766051 isParatext "false" @default.
• W3033766051 isRetracted "false" @default.
• W3033766051 magId "3033766051" @default.
• W3033766051 workType "article" @default.