FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3033888938> ?p ?o ?g. }

• W3033888938 endingPage "109410" @default.
• W3033888938 startingPage "109410" @default.
• W3033888938 abstract "Gut microbiome has been proven to be involved in the development of type 2 diabetes (T2D). Additionally, increasing evidence showed that the composition of gut microbiome is highly associated with the outcome of T2D therapy. Previously we demonstrated that feruloylated oligosaccharides (FOs) and ferulic acid (FA) alleviated diabetic syndrome in rats, but the detailed mechanism has not been explored yet. In this study we strived to characterize how FOs and FA altered the gut microbiome and related metabolome in diabetic rats by using high-throughput sequencing of 16S rRNA and gas chromatography (GC). Our results showed that FOs reduced the abundance of Lactobacillus, Ruminococcus, Oscillibacter, and Desulfovibrio, but increased the abundance of Akkermansia, Phascolarctobacterium and Turicibacter. The structure of gut microbiome in FOs treated rats was similar with healthy rats rather than diabetic rats. Likewise, FA decreased the portion of Lactobacillus, Ruminococcus, but promoted the growth of Bacteroides, Blautia, Faecalibacterium, Parabacteroides and Phascolarctobacterium. Additionally, the short-chain fatty acids (SCFAs) and branched-chain fatty acids (BCFAs), the main bacterial lipid metabolites in gut mediating host glucose metabolism, was dramatically elevated along with FOs and FA treatment. Our findings indicated that FOs and FA attenuated diabetic syndrome in rats most likely by modulating the composition and metabolism of gut microbiome. The study gives new insight into the mechanism underlying the anti-diabetes effect of functional foods as well as facilitates the development of dietary supplements for diabetic patients." @default.
• W3033888938 created "2020-06-12" @default.
• W3033888938 creator A5004417369 @default.
• W3033888938 creator A5008634841 @default.
• W3033888938 creator A5011349676 @default.
• W3033888938 creator A5030684803 @default.
• W3033888938 creator A5030744177 @default.
• W3033888938 creator A5068500818 @default.
• W3033888938 date "2020-11-01" @default.
• W3033888938 modified "2023-10-12" @default.
• W3033888938 title "Feruloylated oligosaccharides and ferulic acid alter gut microbiome to alleviate diabetic syndrome" @default.
• W3033888938 cites W1524070096 @default.
• W3033888938 cites W1647551795 @default.
• W3033888938 cites W1793035576 @default.
• W3033888938 cites W1856033750 @default.
• W3033888938 cites W1965532248 @default.
• W3033888938 cites W1968659063 @default.
• W3033888938 cites W1971415551 @default.
• W3033888938 cites W1980132875 @default.
• W3033888938 cites W1984127982 @default.
• W3033888938 cites W1986215448 @default.
• W3033888938 cites W1989243836 @default.
• W3033888938 cites W2023615726 @default.
• W3033888938 cites W2024709671 @default.
• W3033888938 cites W2036057672 @default.
• W3033888938 cites W2037759895 @default.
• W3033888938 cites W2043019177 @default.
• W3033888938 cites W2071841602 @default.
• W3033888938 cites W2083231447 @default.
• W3033888938 cites W2100209194 @default.
• W3033888938 cites W2115396284 @default.
• W3033888938 cites W2116442793 @default.
• W3033888938 cites W2135989088 @default.
• W3033888938 cites W2149515881 @default.
• W3033888938 cites W2149897979 @default.
• W3033888938 cites W2154660883 @default.
• W3033888938 cites W2163751788 @default.
• W3033888938 cites W2167062509 @default.
• W3033888938 cites W2290110623 @default.
• W3033888938 cites W2321624725 @default.
• W3033888938 cites W2325841985 @default.
• W3033888938 cites W2361807195 @default.
• W3033888938 cites W2396003270 @default.
• W3033888938 cites W2502576340 @default.
• W3033888938 cites W2574087792 @default.
• W3033888938 cites W2609398719 @default.
• W3033888938 cites W2758183934 @default.
• W3033888938 cites W2768439022 @default.
• W3033888938 cites W2781690695 @default.
• W3033888938 cites W2785703267 @default.
• W3033888938 cites W2789893336 @default.
• W3033888938 cites W2802802305 @default.
• W3033888938 cites W2928916577 @default.
• W3033888938 cites W2935703279 @default.
• W3033888938 cites W2958641732 @default.
• W3033888938 cites W2989815310 @default.
• W3033888938 cites W4211058450 @default.
• W3033888938 cites W4250753126 @default.
• W3033888938 doi "https://doi.org/10.1016/j.foodres.2020.109410" @default.
• W3033888938 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33233097" @default.
• W3033888938 hasPublicationYear "2020" @default.
• W3033888938 type Work @default.
• W3033888938 sameAs 3033888938 @default.
• W3033888938 citedByCount "61" @default.
• W3033888938 countsByYear W30338889382020 @default.
• W3033888938 countsByYear W30338889382021 @default.
• W3033888938 countsByYear W30338889382022 @default.
• W3033888938 countsByYear W30338889382023 @default.
• W3033888938 crossrefType "journal-article" @default.
• W3033888938 hasAuthorship W3033888938A5004417369 @default.
• W3033888938 hasAuthorship W3033888938A5008634841 @default.
• W3033888938 hasAuthorship W3033888938A5011349676 @default.
• W3033888938 hasAuthorship W3033888938A5030684803 @default.
• W3033888938 hasAuthorship W3033888938A5030744177 @default.
• W3033888938 hasAuthorship W3033888938A5068500818 @default.
• W3033888938 hasConcept C143121216 @default.
• W3033888938 hasConcept C185592680 @default.
• W3033888938 hasConcept C2780213334 @default.
• W3033888938 hasConcept C3019978661 @default.
• W3033888938 hasConcept C31903555 @default.
• W3033888938 hasConcept C539455810 @default.
• W3033888938 hasConcept C55493867 @default.
• W3033888938 hasConcept C60644358 @default.
• W3033888938 hasConcept C86803240 @default.
• W3033888938 hasConceptScore W3033888938C143121216 @default.
• W3033888938 hasConceptScore W3033888938C185592680 @default.
• W3033888938 hasConceptScore W3033888938C2780213334 @default.
• W3033888938 hasConceptScore W3033888938C3019978661 @default.
• W3033888938 hasConceptScore W3033888938C31903555 @default.
• W3033888938 hasConceptScore W3033888938C539455810 @default.
• W3033888938 hasConceptScore W3033888938C55493867 @default.
• W3033888938 hasConceptScore W3033888938C60644358 @default.
• W3033888938 hasConceptScore W3033888938C86803240 @default.
• W3033888938 hasLocation W30338889381 @default.
• W3033888938 hasOpenAccess W3033888938 @default.
• W3033888938 hasPrimaryLocation W30338889381 @default.
• W3033888938 hasRelatedWork W1122953082 @default.
• W3033888938 hasRelatedWork W2509550348 @default.

• next