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- W3033891605 abstract "Abstract Two novel mixed-ligand coordination polymers, {[Co(tdc)(btrp)]·0.67DMF} n (1) and {[Zn 2 (bimb) 2 (tdc) 2 ]·2H 2 O} n (2) involving 2,5-thiophenedicarboxylate (H 2 tdc), and bitopic flexible N-donor ligands, 1,3-bis(1,2,4-triazol-1-yl)propane (btrp) and 1,4-bis((1 H -benzo[ d ]imidazol-1-yl)methyl)benzene (bimb), have been synthesized by the hydrothermal method and characterized via IR, elemental analysis, thermal analysis, and powder X-ray diffraction. The biological functional studies were performed; the treatment activity of the compounds on periodontitis and the specific mechanism was explored. First, the real-time RT-PCR was carried out to determine the inflammatory genes nf-κb and p53 relative expression in periodontal mucosal cells after treating with compounds 1 and 2 . Then, the level of the inflammatory cytokine in the gingival crevicular fluid after treating with compounds was also determined by the ELISA detection kit." @default.
- W3033891605 created "2020-06-12" @default.
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- W3033891605 date "2020-04-21" @default.
- W3033891605 modified "2023-10-14" @default.
- W3033891605 title "Two mixed-ligand coordination polymers based on 2,5-thiophenedicarboxylic acid and flexible N-donor ligands: the protective effect on periodontitis via reducing the release of IL-1β and TNF-α" @default.
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- W3033891605 doi "https://doi.org/10.1515/chem-2020-0081" @default.
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