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- W3033938213 abstract "The use of lumen-apposing metal stent (LAMS) for drainage of pancreatic fluid collections (PFCs) has gained increasing popularity because of high clinical and technical success. It is supposed that LAMS has lower risk of migration since it has two large flanges with antimigratory features. However, there is lack of robust data supporting this advantage over conventional biliary covered self-expanding metal stents (CSEMS), which is also effective and safe. Therefore, the aim of this study is to compare LAMS versus CSEMS to evaluate migration rates. This is an ongoing randomized, controlled, open label trial in a tertiary therapeutic endoscopy center. Only symptomatic patients or patients with infected PFCs have been recruited. Interim analysis is presented. Characteristics of the initial 25 patients enrolled are summarized in table 1. Thirteen subjects were randomized to CSEMS and 12 for LAMS with no statistical difference between the groups. Technical success was not achieved in only two cases of LAMS (100% vs 83.3%; p=0.78), due to stent misdeployment. Both cases were successfully treated with placement of a CSEMS through the malpositioned LAMS. There was one mild adverse event (bleeding), in a procedure using LAMS. Necrosectomy or lavage of the cavity were necessary in 12 PFCs, six in each group. Accidental displacement of the stent occured in two necrosectomies. Stent migration was detected in only one subject of the CSEMS arm (p=1.0). Despite the considerable amount of articles addressing the use of LAMS in PFCs, its superiority is still conflicting in a few aspects. Some centers reported that the indication should be carefully reviewed by multidisciplinary opinion and based on the characteristics of the patient. To our knowledge, this is the first trial assessing migration as primary outcome. Our interim analysis suggests that stent migration was not different comparing LAMS and CSEMS. However, LAMS can be less cumbersome to access the collection for necrosectomy." @default.
- W3033938213 created "2020-06-12" @default.
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- W3033938213 date "2020-06-01" @default.
- W3033938213 modified "2023-09-25" @default.
- W3033938213 title "Su1313 COMPARISON OF MIGRATION RATE OF LUMEN-APPOSING METAL STENT AND STANDARD COVERED SELF-EXPANDING METAL STENT FOR ENDOSCOPIC ULTRASOUND-GUIDED PANCREATIC FLUID COLLECTION DRAINAGE: A RANDOMIZED CONTROLLED TRIAL" @default.
- W3033938213 doi "https://doi.org/10.1016/j.gie.2020.03.2159" @default.
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