FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3033976424> ?p ?o ?g. }

• W3033976424 endingPage "726" @default.
• W3033976424 startingPage "715" @default.
• W3033976424 abstract "Ketamine exerts rapid antidepressant action in depressed and treatment-resistant depressed patients within hours. At the same time, ketamine elicits a unique form of functional synaptic plasticity that shares several attributes and molecular mechanisms with well-characterized forms of homeostatic synaptic scaling. Lithium is a widely used mood stabilizer also proposed to act via synaptic scaling for its antimanic effects. Several studies to date have identified specific forms of homeostatic synaptic plasticity that are elicited by these drugs used to treat neuropsychiatric disorders. In the last two decades, extensive work on homeostatic synaptic plasticity mechanisms have shown that they diverge from classical synaptic plasticity mechanisms that process and store information and thus present a novel avenue for synaptic regulation with limited direct interference with cognitive processes. In this review, we discuss the intersection of the findings from neuropsychiatric treatments and homeostatic plasticity studies to highlight a potentially wider paradigm for treatment advance. Ketamine exerts rapid antidepressant action in depressed and treatment-resistant depressed patients within hours. At the same time, ketamine elicits a unique form of functional synaptic plasticity that shares several attributes and molecular mechanisms with well-characterized forms of homeostatic synaptic scaling. Lithium is a widely used mood stabilizer also proposed to act via synaptic scaling for its antimanic effects. Several studies to date have identified specific forms of homeostatic synaptic plasticity that are elicited by these drugs used to treat neuropsychiatric disorders. In the last two decades, extensive work on homeostatic synaptic plasticity mechanisms have shown that they diverge from classical synaptic plasticity mechanisms that process and store information and thus present a novel avenue for synaptic regulation with limited direct interference with cognitive processes. In this review, we discuss the intersection of the findings from neuropsychiatric treatments and homeostatic plasticity studies to highlight a potentially wider paradigm for treatment advance." @default.
• W3033976424 created "2020-06-12" @default.
• W3033976424 creator A5055334509 @default.
• W3033976424 creator A5059395438 @default.
• W3033976424 date "2020-06-01" @default.
• W3033976424 modified "2023-10-18" @default.
• W3033976424 title "Targeting Homeostatic Synaptic Plasticity for Treatment of Mood Disorders" @default.
• W3033976424 cites W1486714645 @default.
• W3033976424 cites W1514853588 @default.
• W3033976424 cites W1542136448 @default.
• W3033976424 cites W1733248925 @default.
• W3033976424 cites W1763478481 @default.
• W3033976424 cites W1965265446 @default.
• W3033976424 cites W1977434210 @default.
• W3033976424 cites W1979957972 @default.
• W3033976424 cites W1980049394 @default.
• W3033976424 cites W1981097208 @default.
• W3033976424 cites W1984167101 @default.
• W3033976424 cites W1986627859 @default.
• W3033976424 cites W1988011192 @default.
• W3033976424 cites W1989198121 @default.
• W3033976424 cites W1989598267 @default.
• W3033976424 cites W1991979408 @default.
• W3033976424 cites W1993568457 @default.
• W3033976424 cites W1994875311 @default.
• W3033976424 cites W1995175184 @default.
• W3033976424 cites W1997602725 @default.
• W3033976424 cites W2000124573 @default.
• W3033976424 cites W2002364516 @default.
• W3033976424 cites W2003137201 @default.
• W3033976424 cites W2009020263 @default.
• W3033976424 cites W2010157600 @default.
• W3033976424 cites W2013319759 @default.
• W3033976424 cites W2015701831 @default.
• W3033976424 cites W2020785500 @default.
• W3033976424 cites W2021431498 @default.
• W3033976424 cites W2022474992 @default.
• W3033976424 cites W2022959185 @default.
• W3033976424 cites W2023081218 @default.
• W3033976424 cites W2025011598 @default.
• W3033976424 cites W2029657904 @default.
• W3033976424 cites W2031543773 @default.
• W3033976424 cites W2031779883 @default.
• W3033976424 cites W2031785254 @default.
• W3033976424 cites W2031898618 @default.
• W3033976424 cites W2033919519 @default.
• W3033976424 cites W2039655932 @default.
• W3033976424 cites W2050066016 @default.
• W3033976424 cites W2050519369 @default.
• W3033976424 cites W2052228724 @default.
• W3033976424 cites W2052757974 @default.
• W3033976424 cites W2053472601 @default.
• W3033976424 cites W2054091111 @default.
• W3033976424 cites W2057845292 @default.
• W3033976424 cites W2060936720 @default.
• W3033976424 cites W2065857393 @default.
• W3033976424 cites W2066781880 @default.
• W3033976424 cites W2069732451 @default.
• W3033976424 cites W2074581529 @default.
• W3033976424 cites W2076077022 @default.
• W3033976424 cites W2077907470 @default.
• W3033976424 cites W2078246734 @default.
• W3033976424 cites W2080611091 @default.
• W3033976424 cites W2091865834 @default.
• W3033976424 cites W2092597282 @default.
• W3033976424 cites W2094730014 @default.
• W3033976424 cites W2094905581 @default.
• W3033976424 cites W2096681544 @default.
• W3033976424 cites W2099503180 @default.
• W3033976424 cites W2109334244 @default.
• W3033976424 cites W2111501348 @default.
• W3033976424 cites W2116190619 @default.
• W3033976424 cites W2118815581 @default.
• W3033976424 cites W2124161234 @default.
• W3033976424 cites W2124203952 @default.
• W3033976424 cites W2135286498 @default.
• W3033976424 cites W2139372806 @default.
• W3033976424 cites W2140382995 @default.
• W3033976424 cites W2142197455 @default.
• W3033976424 cites W2142303954 @default.
• W3033976424 cites W2145216601 @default.
• W3033976424 cites W2152668149 @default.
• W3033976424 cites W2155758917 @default.
• W3033976424 cites W2155760129 @default.
• W3033976424 cites W2156940776 @default.
• W3033976424 cites W2166563700 @default.
• W3033976424 cites W2167150855 @default.
• W3033976424 cites W2168028420 @default.
• W3033976424 cites W2168570529 @default.
• W3033976424 cites W2168976498 @default.
• W3033976424 cites W2301435817 @default.
• W3033976424 cites W2470713557 @default.
• W3033976424 cites W2521319993 @default.
• W3033976424 cites W2573194853 @default.
• W3033976424 cites W2578432118 @default.
• W3033976424 cites W2583421592 @default.
• W3033976424 cites W2585275288 @default.
• W3033976424 cites W2586049557 @default.

• next