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• W3033995094 abstract "Abstract Previous evidence suggests different cortical areas naturally oscillate at distinct frequencies, reflecting tuning properties of each region. The concurrent use of transcranial magnetic stimulation (TMS) and electroencephalography (EEG) has been used to perturb cortical regions, resulting in an observed post-stimulation response that is maximal at the natural frequency of that region. However, little is known about the spatial extent of TMS-induced activation differences in cortical regions when comparing resting state (passive) versus active task performance. Here, we employed TMS-EEG to directly perturb three cortical areas in the right hemisphere while measuring the resultant changes in maximal evoked frequency in healthy human subjects during a resting state (N=12) and during an active sensorimotor task (N=12). Our results revealed that the brain engages a higher dominant frequency mode when actively engaged in a task, such that the frequency evoked during a task is consistently higher across cortical regions, regardless of the region stimulated. These findings suggest that a distinct characteristic of active performance versus resting state is a higher state of natural cortical frequencies." @default.
• W3033995094 created "2020-06-12" @default.
• W3033995094 creator A5021965223 @default.
• W3033995094 creator A5045790815 @default.
• W3033995094 date "2019-04-22" @default.
• W3033995094 modified "2023-09-26" @default.
• W3033995094 title "State-dependent differences in the frequency of TMS-evoked potentials between resting and active states" @default.
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• W3033995094 doi "https://doi.org/10.1101/614826" @default.
• W3033995094 hasPublicationYear "2019" @default.
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