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- W3034177453 abstract "• Increased butanol tolerance may improve its potential for bacterial production of butanol. • Active efflux is one of the less often described mechanisms of butanol tolerance. • Specific butanol efflux pumps are described in Gram-negative bacteria. • In Gram-positive bacteria, evidence of butanol efflux was summarized. • Potential of efflux pumps in butanol production was discussed. N-butanol, a valued solvent and potential fuel extender, could possibly be produced by fermentation using either native producers, i.e. solventogenic Clostridia, or engineered platform organisms such as Escherichia coli or Pseudomonas species, if the main process obstacle, a low final butanol concentration, could be overcome. A low final concentration of butanol is the result of its high toxicity to production cells. Nevertheless, bacteria have developed several mechanisms to cope with this toxicity and one of them is active butanol efflux. This review presents information about a few well characterized butanol efflux pumps from Gram-negative bacteria ( P. putida and E. coli ) and summarizes knowledge about putative butanol efflux systems in Gram-positive bacteria." @default.
- W3034177453 created "2020-06-19" @default.
- W3034177453 creator A5005877620 @default.
- W3034177453 creator A5037323157 @default.
- W3034177453 date "2020-08-01" @default.
- W3034177453 modified "2023-09-23" @default.
- W3034177453 title "Role of efflux in enhancing butanol tolerance of bacteria" @default.
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