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- W3034206304 abstract "Post-surgical adhesions are a major complication leading to organ dysfunctions, pain, intestinal obstruction, and infertility. The incidence of post-surgical adhesion is really high. The factors involved in the pathogenesis of post-surgical fibrosis, are largely unknown, for example why two patients with similar abdominal operation have a different risks of adhesion severity? High secretion of pro-inflammatory cytokines and growth factors, includes tumour necrosis factor α (TNF-α), interleukin 6 (IL6), and transforming growth factor β (TGF-β) by persistent recruitment of immune cells and the inappropriate proliferated fibroblast/mesothelial cells can stimulate signalling pathways particularly TGF-β leads to the up-regulation of some pro-fibrotic genes that impair fibrinolytic activity and promote extracellular matrix (ECM) accumulation. In this review, we focus on the role of diabetes and hyperglycaemia on post-surgical fibrosis, including the molecular mechanisms affected by hyperglycaemia that cause inflammation, oxidative stress, and increase the expression of pro-fibrotic molecules." @default.
- W3034206304 created "2020-06-19" @default.
- W3034206304 creator A5038854437 @default.
- W3034206304 creator A5058049728 @default.
- W3034206304 creator A5089967609 @default.
- W3034206304 date "2020-06-13" @default.
- W3034206304 modified "2023-10-18" @default.
- W3034206304 title "Hyperglycaemia and the risk of post-surgical adhesion" @default.
- W3034206304 cites W1529592271 @default.
- W3034206304 cites W1594856996 @default.
- W3034206304 cites W1786861597 @default.
- W3034206304 cites W1965585969 @default.
- W3034206304 cites W1966419887 @default.
- W3034206304 cites W1966621383 @default.
- W3034206304 cites W1968699748 @default.
- W3034206304 cites W1971393959 @default.
- W3034206304 cites W1971784328 @default.
- W3034206304 cites W1974942503 @default.
- W3034206304 cites W1975105798 @default.
- W3034206304 cites W1975812938 @default.
- W3034206304 cites W1979934328 @default.
- W3034206304 cites W1989101440 @default.
- W3034206304 cites W1991647666 @default.
- W3034206304 cites W1992091136 @default.
- W3034206304 cites W1994812539 @default.
- W3034206304 cites W1999472351 @default.
- W3034206304 cites W2004279808 @default.
- W3034206304 cites W2009668180 @default.
- W3034206304 cites W2011019446 @default.
- W3034206304 cites W2014483782 @default.
- W3034206304 cites W2024652937 @default.
- W3034206304 cites W2025620210 @default.
- W3034206304 cites W2036127346 @default.
- W3034206304 cites W2039878888 @default.
- W3034206304 cites W2040661588 @default.
- W3034206304 cites W2046768393 @default.
- W3034206304 cites W2054389519 @default.
- W3034206304 cites W2055168506 @default.
- W3034206304 cites W2057537453 @default.
- W3034206304 cites W2059816649 @default.
- W3034206304 cites W2060895623 @default.
- W3034206304 cites W2064297038 @default.
- W3034206304 cites W2070732456 @default.
- W3034206304 cites W2071073097 @default.
- W3034206304 cites W2072435204 @default.
- W3034206304 cites W2072878932 @default.
- W3034206304 cites W2074266524 @default.
- W3034206304 cites W2074865203 @default.
- W3034206304 cites W2077689041 @default.
- W3034206304 cites W2081240175 @default.
- W3034206304 cites W2084141237 @default.
- W3034206304 cites W2086128459 @default.
- W3034206304 cites W2086327676 @default.
- W3034206304 cites W2094642452 @default.
- W3034206304 cites W2097705853 @default.
- W3034206304 cites W2098977755 @default.
- W3034206304 cites W2105810016 @default.
- W3034206304 cites W2108762011 @default.
- W3034206304 cites W2110582342 @default.
- W3034206304 cites W2118170059 @default.
- W3034206304 cites W2119329939 @default.
- W3034206304 cites W2122017924 @default.
- W3034206304 cites W2123560318 @default.
- W3034206304 cites W2124555253 @default.
- W3034206304 cites W2128048856 @default.
- W3034206304 cites W2132203967 @default.
- W3034206304 cites W2136294641 @default.
- W3034206304 cites W2138928713 @default.
- W3034206304 cites W2143104968 @default.
- W3034206304 cites W2143902746 @default.
- W3034206304 cites W2145002455 @default.
- W3034206304 cites W2145047965 @default.
- W3034206304 cites W2147068335 @default.
- W3034206304 cites W2149617435 @default.
- W3034206304 cites W2151258395 @default.
- W3034206304 cites W2155456675 @default.
- W3034206304 cites W2159229970 @default.
- W3034206304 cites W2167213027 @default.
- W3034206304 cites W2168524778 @default.
- W3034206304 cites W2169961704 @default.
- W3034206304 cites W2179490659 @default.
- W3034206304 cites W2257615562 @default.
- W3034206304 cites W2319168424 @default.
- W3034206304 cites W2334955683 @default.
- W3034206304 cites W2400166575 @default.
- W3034206304 cites W2515189190 @default.
- W3034206304 cites W2525683625 @default.
- W3034206304 cites W2763481019 @default.
- W3034206304 cites W2886711020 @default.
- W3034206304 cites W3009180312 @default.
- W3034206304 doi "https://doi.org/10.1080/13813455.2020.1776330" @default.
- W3034206304 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32536284" @default.
- W3034206304 hasPublicationYear "2020" @default.
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