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- W3034310018 abstract "The term is certainly one of the oldest medical terms still in use. However, its meaning has changed over the centuries. This work gives a historical and critical review of the concept of inflammation, with special reference to kidney diseases. Over time the definition of inflammation has shifted from a pure collection of symptoms to a histopathological definition, characterized by the tissue and different subcategories according to the cell type involved. The advantages of this classification are the generally good response to corticosteroids (with only a few exceptions) and the availability of specific drugs for each infiltrate. Finally, a molecular definition of inflammation has arisen, where the infiltrates make room to a plethora of plasma mediators. The authors show that the use of plasma biomarkers as a tool to define state leads to net inflation of the number of inflammatory diseases - an effect that shows clearly in the field of nephrology." @default.
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- W3034310018 date "2020-06-10" @default.
- W3034310018 modified "2023-09-23" @default.
- W3034310018 title "Inflammation in kidney diseases" @default.
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