FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3034374100> ?p ?o ?g. }

• W3034374100 endingPage "1752" @default.
• W3034374100 startingPage "1752" @default.
• W3034374100 abstract "Nutraceuticals include a wide variety of bioactive compounds, such as polyphenols, which have been highlighted for their remarkable health benefits. Specially, maqui berries have shown great antioxidant activity and anti-inflammatory effects on some inflammatory diseases. The objectives of the present study were to explore the therapeutic effects of maqui berries on acute-phase inflammation in Crohn’s disease. Balb/c mice were exposed to 2,4,6-trinitrobenzene sulfonic acid (TNBS) via intracolonic administration. Polyphenolic maqui extract (Ach) was administered orally daily for 4 days after TNBS induction (Curative Group), and for 7 days prior to the TNBS induction until sacrifice (Preventive Group). Our results showed that both preventive and curative Ach administration inhibited body weight loss and colon shortening, and attenuated the macroscopic and microscopic damage signs, as well as significantly reducing transmural inflammation and boosting the recovery of the mucosal architecture and its muco-secretory function. Additionally, Ach promotes macrophage polarization to the M2 phenotype and was capable of down-regulating significantly the expression of inflammatory proteins COX-2 and iNOS, and at the same time it regulates the antioxidant Nrf-2/HO-1 pathway. In conclusion, this is the first study in which it is demonstrated that the properties of Ach as could be used as a preventive and curative treatment in Crohn’s disease." @default.
• W3034374100 created "2020-06-19" @default.
• W3034374100 creator A5003579126 @default.
• W3034374100 creator A5023578723 @default.
• W3034374100 creator A5025098898 @default.
• W3034374100 creator A5048414219 @default.
• W3034374100 creator A5049257513 @default.
• W3034374100 creator A5049590246 @default.
• W3034374100 creator A5073113433 @default.
• W3034374100 creator A5073814072 @default.
• W3034374100 creator A5081520322 @default.
• W3034374100 creator A5091855686 @default.
• W3034374100 date "2020-06-11" @default.
• W3034374100 modified "2023-10-18" @default.
• W3034374100 title "Polyphenolic Maqui Extract as a Potential Nutraceutical to Treat TNBS-Induced Crohn’s Disease by the Regulation of Antioxidant and Anti-Inflammatory Pathways" @default.
• W3034374100 cites W1964652297 @default.
• W3034374100 cites W1973907050 @default.
• W3034374100 cites W2014335125 @default.
• W3034374100 cites W2028078823 @default.
• W3034374100 cites W2037809991 @default.
• W3034374100 cites W2041085522 @default.
• W3034374100 cites W2051591207 @default.
• W3034374100 cites W2060556615 @default.
• W3034374100 cites W2067080507 @default.
• W3034374100 cites W2069580163 @default.
• W3034374100 cites W2085558039 @default.
• W3034374100 cites W2102094913 @default.
• W3034374100 cites W2129503957 @default.
• W3034374100 cites W2142055693 @default.
• W3034374100 cites W2209452051 @default.
• W3034374100 cites W2210304681 @default.
• W3034374100 cites W2260702953 @default.
• W3034374100 cites W2294422794 @default.
• W3034374100 cites W2313451883 @default.
• W3034374100 cites W2322979423 @default.
• W3034374100 cites W2340338776 @default.
• W3034374100 cites W2405666752 @default.
• W3034374100 cites W2491549472 @default.
• W3034374100 cites W2518441479 @default.
• W3034374100 cites W2556315980 @default.
• W3034374100 cites W2562373507 @default.
• W3034374100 cites W2562537703 @default.
• W3034374100 cites W2582591980 @default.
• W3034374100 cites W2583548519 @default.
• W3034374100 cites W2594848814 @default.
• W3034374100 cites W2730120915 @default.
• W3034374100 cites W2731851704 @default.
• W3034374100 cites W2755481361 @default.
• W3034374100 cites W2766046358 @default.
• W3034374100 cites W2782685575 @default.
• W3034374100 cites W2787655174 @default.
• W3034374100 cites W2787860404 @default.
• W3034374100 cites W2794921186 @default.
• W3034374100 cites W2802759699 @default.
• W3034374100 cites W2810650444 @default.
• W3034374100 cites W2846061873 @default.
• W3034374100 cites W2883635247 @default.
• W3034374100 cites W2886680745 @default.
• W3034374100 cites W2888604741 @default.
• W3034374100 cites W2895814849 @default.
• W3034374100 cites W2896568378 @default.
• W3034374100 cites W2905350538 @default.
• W3034374100 cites W2906626342 @default.
• W3034374100 cites W2912712165 @default.
• W3034374100 cites W2939717249 @default.
• W3034374100 cites W2953119997 @default.
• W3034374100 cites W2955504961 @default.
• W3034374100 cites W2968014044 @default.
• W3034374100 cites W2970129847 @default.
• W3034374100 cites W2973156043 @default.
• W3034374100 cites W2985172286 @default.
• W3034374100 cites W3014868305 @default.
• W3034374100 cites W4293247451 @default.
• W3034374100 doi "https://doi.org/10.3390/nu12061752" @default.
• W3034374100 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7353344" @default.
• W3034374100 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32545398" @default.
• W3034374100 hasPublicationYear "2020" @default.
• W3034374100 type Work @default.
• W3034374100 sameAs 3034374100 @default.
• W3034374100 citedByCount "12" @default.
• W3034374100 countsByYear W30343741002021 @default.
• W3034374100 countsByYear W30343741002022 @default.
• W3034374100 countsByYear W30343741002023 @default.
• W3034374100 crossrefType "journal-article" @default.
• W3034374100 hasAuthorship W3034374100A5003579126 @default.
• W3034374100 hasAuthorship W3034374100A5023578723 @default.
• W3034374100 hasAuthorship W3034374100A5025098898 @default.
• W3034374100 hasAuthorship W3034374100A5048414219 @default.
• W3034374100 hasAuthorship W3034374100A5049257513 @default.
• W3034374100 hasAuthorship W3034374100A5049590246 @default.
• W3034374100 hasAuthorship W3034374100A5073113433 @default.
• W3034374100 hasAuthorship W3034374100A5073814072 @default.
• W3034374100 hasAuthorship W3034374100A5081520322 @default.
• W3034374100 hasAuthorship W3034374100A5091855686 @default.
• W3034374100 hasBestOaLocation W30343741001 @default.
• W3034374100 hasConcept C126322002 @default.
• W3034374100 hasConcept C142724271 @default.
• W3034374100 hasConcept C17857428 @default.

• next