Matches in SemOpenAlex for { <https://semopenalex.org/work/W3034482014> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W3034482014 endingPage "106208" @default.
- W3034482014 startingPage "106208" @default.
- W3034482014 abstract "Abstract By using the saturation shake-flask method, the saturated solubility of bezafibrate in neat water, methanol, ethanol, n-propanol and isopropanol and aqueous co-solvent mixtures of methanol (1) + water (2), ethanol (1) + water (2), isopropanol (1) + water (2) and n-propanol (1) + water (2) was experimentally acquired at temperatures from 283.15 Kto 323.15 K and local atmospheric pressure. The maximum solubility magnitudes in mole fraction were recorded in the neat solvents of methanol/ethanol/n-propanol/isopropanol for corresponding solutions. The mole fraction solubility was described mathematically by using the van’t Hoff-Jouyban-Acree and Jouyban-Acree models. The largest value of relative average deviations was 6.23%; and, root-mean-square deviations, 8.92 × 10−5. The local mole fractions of water and co-solvent (methanol, ethanol, n-propanol or isopropanol) around the drug bezafibrate were quantitatively investigated by the use of Inverse Kirkwood–Buff integrals method. Results indicated that the bezafibrate was preferentially solvated by methanol (ethanol, n-propanol or isopropanol) in alcohol-rich and intermediate compositions in the alcohol mixtures; while in water-rich compositions, bezafibrate was preferentially solvated by water. The main factors relating to solvent effect were inspected through Kamlet and Taft linear solvation energy relationships, demonstrating that the cavity formation energy and dipolarity-polarizability in methanol solutions, cavity formation energy and basicity in ethanol solutions, and cavity formation energy in n-propanol (isopropanol) solutions played the principal role upon the bezafibrate solubility variation." @default.
- W3034482014 created "2020-06-19" @default.
- W3034482014 creator A5003710372 @default.
- W3034482014 creator A5025855204 @default.
- W3034482014 creator A5034321189 @default.
- W3034482014 creator A5082778481 @default.
- W3034482014 date "2021-05-01" @default.
- W3034482014 modified "2023-10-18" @default.
- W3034482014 title "Bezafibrate in several aqueous mixtures of low alcohols: Solubility, solvent effect and preferential solvation" @default.
- W3034482014 cites W1980825543 @default.
- W3034482014 cites W1987825764 @default.
- W3034482014 cites W2029807337 @default.
- W3034482014 cites W2034200280 @default.
- W3034482014 cites W2055914734 @default.
- W3034482014 cites W2065203743 @default.
- W3034482014 cites W2082947065 @default.
- W3034482014 cites W2089049959 @default.
- W3034482014 cites W2094246322 @default.
- W3034482014 cites W2219083286 @default.
- W3034482014 cites W2416583393 @default.
- W3034482014 cites W2473163679 @default.
- W3034482014 cites W2512202260 @default.
- W3034482014 cites W2529856339 @default.
- W3034482014 cites W2542068968 @default.
- W3034482014 cites W2542762086 @default.
- W3034482014 cites W2557954647 @default.
- W3034482014 cites W2613909139 @default.
- W3034482014 cites W2895101345 @default.
- W3034482014 cites W2904307822 @default.
- W3034482014 cites W2954960840 @default.
- W3034482014 cites W2959197649 @default.
- W3034482014 cites W2979258269 @default.
- W3034482014 cites W2981526016 @default.
- W3034482014 cites W3004261297 @default.
- W3034482014 cites W3004356472 @default.
- W3034482014 cites W4210449401 @default.
- W3034482014 cites W4230071610 @default.
- W3034482014 cites W4248107770 @default.
- W3034482014 cites W4300720636 @default.
- W3034482014 cites W2885848695 @default.
- W3034482014 doi "https://doi.org/10.1016/j.jct.2020.106208" @default.
- W3034482014 hasPublicationYear "2021" @default.
- W3034482014 type Work @default.
- W3034482014 sameAs 3034482014 @default.
- W3034482014 citedByCount "12" @default.
- W3034482014 countsByYear W30344820142021 @default.
- W3034482014 countsByYear W30344820142022 @default.
- W3034482014 countsByYear W30344820142023 @default.
- W3034482014 crossrefType "journal-article" @default.
- W3034482014 hasAuthorship W3034482014A5003710372 @default.
- W3034482014 hasAuthorship W3034482014A5025855204 @default.
- W3034482014 hasAuthorship W3034482014A5034321189 @default.
- W3034482014 hasAuthorship W3034482014A5082778481 @default.
- W3034482014 hasConcept C132439834 @default.
- W3034482014 hasConcept C148093993 @default.
- W3034482014 hasConcept C155574463 @default.
- W3034482014 hasConcept C178790620 @default.
- W3034482014 hasConcept C184651966 @default.
- W3034482014 hasConcept C185592680 @default.
- W3034482014 hasConcept C2776362216 @default.
- W3034482014 hasConcept C2780471494 @default.
- W3034482014 hasConcept C55493867 @default.
- W3034482014 hasConceptScore W3034482014C132439834 @default.
- W3034482014 hasConceptScore W3034482014C148093993 @default.
- W3034482014 hasConceptScore W3034482014C155574463 @default.
- W3034482014 hasConceptScore W3034482014C178790620 @default.
- W3034482014 hasConceptScore W3034482014C184651966 @default.
- W3034482014 hasConceptScore W3034482014C185592680 @default.
- W3034482014 hasConceptScore W3034482014C2776362216 @default.
- W3034482014 hasConceptScore W3034482014C2780471494 @default.
- W3034482014 hasConceptScore W3034482014C55493867 @default.
- W3034482014 hasLocation W30344820141 @default.
- W3034482014 hasOpenAccess W3034482014 @default.
- W3034482014 hasPrimaryLocation W30344820141 @default.
- W3034482014 hasRelatedWork W1973267518 @default.
- W3034482014 hasRelatedWork W1986019010 @default.
- W3034482014 hasRelatedWork W2050186274 @default.
- W3034482014 hasRelatedWork W2318131592 @default.
- W3034482014 hasRelatedWork W2324556807 @default.
- W3034482014 hasRelatedWork W2525457520 @default.
- W3034482014 hasRelatedWork W2557747266 @default.
- W3034482014 hasRelatedWork W2992360811 @default.
- W3034482014 hasRelatedWork W3014230148 @default.
- W3034482014 hasRelatedWork W3089392999 @default.
- W3034482014 hasVolume "156" @default.
- W3034482014 isParatext "false" @default.
- W3034482014 isRetracted "false" @default.
- W3034482014 magId "3034482014" @default.
- W3034482014 workType "article" @default.