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- W3034580586 abstract "With the seminal discovery of somatic cell reprogramming with defined genetic factors, it is now a routine laboratory procedure to reprogram somatic cells to generate patient-specific induced pluripotent stem cells (iPSCs) [1] Patient-specific iPSCs can be differentiated to generate mature neurons as well as three-dimensional brain organoids that show appropriate functional activity in electrophysiological studies [2,3]. However, there is a significant gap in the thoughtful incorporation of patient-derived neuronal cells in clinical studies addressing disease risk." @default.
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- W3034580586 date "2020-01-01" @default.
- W3034580586 modified "2023-09-23" @default.
- W3034580586 title "Integrating stem cell-based experiments in clinical research" @default.
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- W3034580586 doi "https://doi.org/10.1192/j.eurpsy.2020.64" @default.
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