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• W3034735181 abstract "El síndrome HELLP (H: hemólisis, EL: enzimas hepáticas elevadas y LP: trombocitopenia) es una forma de preeclampsia (PE) grave. El síndrome puede ser: completo o incompleto (con tres criterios analíticos, o sólo uno o dos); Clase i, ii o iii (según plaquetas < 50.000, 50.000-100.000 o > 100.000/mm3); postparto o anteparto; siendo estos últimos, precoces o tardíos (antes o después de la semana 34 de gestación). Describimos y analizamos las características clínico-analíticas y evolución observadas en embarazadas hipertensas que desarrollaron HELLP. Estudio descriptivo y analítico, observacional, de tipo cohorte retrospectiva; en un período de dos años. Incluyó embarazadas hipertensas que desarrollaron HELLP, durante el curso de su internación en la maternidad de nuestro hospital de atención terciaria. Incluyó 318 embarazadas hipertensas. Se observaron 28 HELLP. La edad materna fue 25,8 ± 7,2 años; la edad gestacional al diagnóstico 31 ± 1 sem. Hubo 4 hipertensas crónicas y 24 hipertensas gestacionales; ocho habían presentado PE en embarazos previos. Hubo 10 síndromes completos y 18 incompletos; de acuerdo a la trombocitopenia, hubo 3 Clase i, 16 Clase ii y 9 Clase iii. La instalación fue posparto en 3 y anteparto en 25: 18 precoces y 7 tardíos. Hubo 17 pacientes que requirieron cuidados intensivos y 10 desarrollaron complicaciones ligadas al HELLP. No se registraron óbitos maternos. La presentación del síndrome fue variable, exhibiéndose mayormente en hipertensas gestacionales con instalación anteparto y precoz. Fue más frecuente la forma incompleta y la trombocitopenia clase ii. Las complicaciones maternas fueron usuales pero no se observaron óbitos. HELLP syndrome (H: hemolysis, EL: elevated liver enzymes and LP: low platelets) is a form of severe preeclampsia (PE). The syndrome can be: complete or incomplete (with three analytical criteria, or only one or two); Class i, ii or iii (according platelets < 50,000; 50,000-100,000 or > 100,000/mm3); postpartum or antepartum; with early or late installation (before or after the 34nd week of gestation). We describe and analyze characteristics and evolution observed in hypertensive pregnant patients who developed HELLP. Retrospective cohort with observation period of two years. It included pregnant hypertensive women who developed HELLP, during the course of their hospitalization in the maternity hospital of our tertiary care hospital. It included 318 hypertensive pregnant women. We observed 28 HELLP. Maternal age was 25.8 ±7.2 years and gestational age at diagnosis 31 ± 1 week. Hypertension was chronic in 4 and gestational in 24; eight had presented PE in the previous pregnancy. There were 10 complete and 18 incomplete syndromes; according to platelet disease there were 3 Class i, 16 Class ii and 9 Class iii. HELLP was postpartum in 3 and antepartum in 25: 18 early and 7 late. There were 17 patients who required intensive care and 10 developed complications linked to HELLP. No maternal deaths were recorded. Presentation was variable, exhibiting mostly in gestational hypertension, antepartum and early. Incomplete form and class II thrombocytopenia were more frequent. Maternal complications were frequent but no deaths were observed." @default.
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• W3034735181 date "2020-10-01" @default.
• W3034735181 modified "2023-09-25" @default.
• W3034735181 title "Síndrome HELLP: características clínicas, analíticas y evolutivas observadas en dos años de experiencia" @default.
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• W3034735181 doi "https://doi.org/10.1016/j.hipert.2020.05.003" @default.
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