FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3034854816> ?p ?o ?g. }

• W3034854816 endingPage "251" @default.
• W3034854816 startingPage "245" @default.
• W3034854816 abstract "Diabetic kidney disease (DKD), a microvascular complication of diabetes, has been the leading cause of end-stage kidney disease (ESKD). Accordingly, patients with type 2 diabetes mellitus (T2DM) develop renal damage due to multiple metabolic and cardiorenal disease-related risk factors, including hyperglycemia, hypertension, dyslipidemia, hyperuricemia, and overnutrition/obesity. Despite multifactorial management including the administration of renin–angiotensin system inhibitors, patients often do not experience sufficient suppression of DKD progression and, thus, remain at risk for ESKD. Recent studies on cardiovascular outcomes among patients with T2DM have clearly shown that sodium–glucose cotransporter 2 (SGLT2) inhibitors, such as empagliflozin, canagliflozin, and dapagliflozin, have cardiorenal protective effects apart from their glucose-lowering effects. In particular, SGLT2 inhibitors have been found to improve renal outcomes, including ESKD, by slowing renal function decline and reducing urinary albumin excretion through their class effect. The proposed mechanisms for the renoprotective effects of SGLT2 inhibitors include the action of tubulo-glomerular feedback system and attenuation of hypoxia and metabolic stress in proximal tubular cells mediated through the inhibition of excessive glucose and sodium reabsorption, increased erythropoiesis, or increased ketone body production." @default.
• W3034854816 created "2020-06-19" @default.
• W3034854816 creator A5035823758 @default.
• W3034854816 creator A5066013649 @default.
• W3034854816 creator A5069516269 @default.
• W3034854816 date "2020-06-11" @default.
• W3034854816 modified "2023-10-18" @default.
• W3034854816 title "Significance of SGLT2 inhibitors: lessons from renal clinical outcomes in patients with type 2 diabetes and basic researches" @default.
• W3034854816 cites W1510069727 @default.
• W3034854816 cites W1888211049 @default.
• W3034854816 cites W1967360868 @default.
• W3034854816 cites W1990025047 @default.
• W3034854816 cites W2001544028 @default.
• W3034854816 cites W2027213678 @default.
• W3034854816 cites W2044773944 @default.
• W3034854816 cites W2056976690 @default.
• W3034854816 cites W2063942799 @default.
• W3034854816 cites W2064130493 @default.
• W3034854816 cites W2086240954 @default.
• W3034854816 cites W2116077357 @default.
• W3034854816 cites W2127854619 @default.
• W3034854816 cites W2133469996 @default.
• W3034854816 cites W2139634859 @default.
• W3034854816 cites W2142830692 @default.
• W3034854816 cites W2146264128 @default.
• W3034854816 cites W2155287847 @default.
• W3034854816 cites W2159511914 @default.
• W3034854816 cites W2164368208 @default.
• W3034854816 cites W2164945237 @default.
• W3034854816 cites W2238341693 @default.
• W3034854816 cites W2338046714 @default.
• W3034854816 cites W2344377904 @default.
• W3034854816 cites W2416348735 @default.
• W3034854816 cites W2424539745 @default.
• W3034854816 cites W2425644022 @default.
• W3034854816 cites W2492672367 @default.
• W3034854816 cites W2519510391 @default.
• W3034854816 cites W2532735232 @default.
• W3034854816 cites W2583476095 @default.
• W3034854816 cites W2604816492 @default.
• W3034854816 cites W2626446274 @default.
• W3034854816 cites W2733849831 @default.
• W3034854816 cites W2772204795 @default.
• W3034854816 cites W2791814181 @default.
• W3034854816 cites W2793450493 @default.
• W3034854816 cites W2794972088 @default.
• W3034854816 cites W2796903473 @default.
• W3034854816 cites W2893445020 @default.
• W3034854816 cites W2900149048 @default.
• W3034854816 cites W2900413769 @default.
• W3034854816 cites W2900442056 @default.
• W3034854816 cites W2917112529 @default.
• W3034854816 cites W2939222610 @default.
• W3034854816 cites W2941801974 @default.
• W3034854816 cites W2948612418 @default.
• W3034854816 cites W2949665037 @default.
• W3034854816 cites W2962851362 @default.
• W3034854816 cites W2965159462 @default.
• W3034854816 cites W2971414122 @default.
• W3034854816 cites W2973242786 @default.
• W3034854816 cites W2981287710 @default.
• W3034854816 cites W2986400602 @default.
• W3034854816 cites W2996130540 @default.
• W3034854816 cites W4206573713 @default.
• W3034854816 doi "https://doi.org/10.1007/s13340-020-00444-8" @default.
• W3034854816 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7387389" @default.
• W3034854816 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32802705" @default.
• W3034854816 hasPublicationYear "2020" @default.
• W3034854816 type Work @default.
• W3034854816 sameAs 3034854816 @default.
• W3034854816 citedByCount "11" @default.
• W3034854816 countsByYear W30348548162020 @default.
• W3034854816 countsByYear W30348548162021 @default.
• W3034854816 countsByYear W30348548162022 @default.
• W3034854816 countsByYear W30348548162023 @default.
• W3034854816 crossrefType "journal-article" @default.
• W3034854816 hasAuthorship W3034854816A5035823758 @default.
• W3034854816 hasAuthorship W3034854816A5066013649 @default.
• W3034854816 hasAuthorship W3034854816A5069516269 @default.
• W3034854816 hasBestOaLocation W30348548162 @default.
• W3034854816 hasConcept C126322002 @default.
• W3034854816 hasConcept C134018914 @default.
• W3034854816 hasConcept C159641895 @default.
• W3034854816 hasConcept C2775887513 @default.
• W3034854816 hasConcept C2776174234 @default.
• W3034854816 hasConcept C2777180221 @default.
• W3034854816 hasConcept C2777422806 @default.
• W3034854816 hasConcept C2778653478 @default.
• W3034854816 hasConcept C2910068830 @default.
• W3034854816 hasConcept C555293320 @default.
• W3034854816 hasConcept C71924100 @default.
• W3034854816 hasConcept C7643261 @default.
• W3034854816 hasConcept C90466245 @default.
• W3034854816 hasConceptScore W3034854816C126322002 @default.
• W3034854816 hasConceptScore W3034854816C134018914 @default.
• W3034854816 hasConceptScore W3034854816C159641895 @default.
• W3034854816 hasConceptScore W3034854816C2775887513 @default.
• W3034854816 hasConceptScore W3034854816C2776174234 @default.

• next