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- W3034874940 abstract "Antiviral innate immunity works as the first line of host defense against viral infection. Pattern recognition receptors (PRRs) and adaptor proteins involved in the innate immune signaling pathways play critical roles in controlling viral infections via the induction of type I interferon and its downstream interferon-stimulated genes. Dynamic changes of adaptor proteins contribute to precise regulation of the activation and shut-off of signaling transduction. While it’s still a mass of complex process in dynamic changes of various protein from host and viruses. In this review, we will summarize the recent progresses on the trafficking patterns and conformational transitions of such adaptors that are involved in the antiviral innate immune signaling pathway during viral DNA sensing. Meanwhile, we aim to dissect the relationships between protein dynamics and DNA sensing antiviral innate immune responses, which will reveal the underlying mechanisms on how to control proteins activity and maintain cell homeostasis. With comprehensive revealing of protein dynamic in cytosolic DNA sensing antiviral innate immune signaling pathway, we will be able to gain potential new targets for the therapies of certain autoimmune diseases." @default.
- W3034874940 created "2020-06-19" @default.
- W3034874940 creator A5038495452 @default.
- W3034874940 date "2020-07-02" @default.
- W3034874940 modified "2023-10-12" @default.
- W3034874940 title "Protein Dynamics in Cytosolic DNA-Sensing Antiviral Innate Immune Signaling Pathways" @default.
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- W3034874940 cites W2002301799 @default.
- W3034874940 cites W2012082059 @default.
- W3034874940 cites W2016131266 @default.
- W3034874940 cites W2029975301 @default.
- W3034874940 cites W2042173485 @default.
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- W3034874940 cites W2137053907 @default.
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- W3034874940 doi "https://doi.org/10.3389/fimmu.2020.01255" @default.
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