FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3034971189> ?p ?o ?g. }

• W3034971189 endingPage "100" @default.
• W3034971189 startingPage "96" @default.
• W3034971189 abstract "Inherited bleeding disorders can lead to lifelong bleeding; they are mainly caused by quantitative or qualitative defect of coagulation factors, von Willebrand factor (VWF) or platelets. No published data are available about the different types of inherited bleeding disorders in Iraq.To describe types, severity and presentation of inherited bleeding disorders in pediatric patients in the major referral center in Iraq.This is a cohort prospective descriptive study conducted at the National Center of Hematology, a referral center for bleeding disorders in Baghdad-Iraq, from January 2015 to December 2019. One hundred ninety-one patients, aged 1 day to 14 years, with suspected inherited bleeding disorder are included in this study. Each patient was interviewed, accompanied by a chaperone, mostly parent(s), with revision of personal and familial bleeding history, conducting a brief medical examination, and withdrawing blood for complete blood count, peripheral blood film, bleeding time, PT and APTT. Further investigations including mixing studies, lupus anticoagulant, clotting factor activity, VWF:antigen (VWF:Ag), VWF: Ristocetin cofactor (VWF:RiCof) and platelet function tests using light transmission aggregometry were performed only if indicated.The mean ± 1SD of age of patients is 5.3 ± 3 years, with a male:female ratio of 1.3:1. Family history of a similar bleeding disorder is recorded in 44.9% patients (P < 0.05). Consanguineous marriage was observed in 70.8% of the families (P < 0.001). The most prevalent inherited bleeding disorder is von Willebrand disease (VWD) (43.9%), of which type 3 is the most common (86.9%). Thrombasthenia is the second most prevalent (39.8%) inherited bleeding disorder; of these, the majority have Glanzmann's thrombasthenia (82.9%). Hemophilia A is found in 9.4% of patients.Type 3 VWD, Glanzmann's thrombasthenia and hemophilia A are the most common inherited bleeding disorders in the central part of Iraq, collectively they constitute >86% of patients. Consanguineous marriage should be discouraged in our society to decrease hereditary bleeding disorders. Also, there is a need to increase awareness and knowledge of bleeding disorders to improve early identification, mitigate the risk of further bleeding and prevent complications." @default.
• W3034971189 created "2020-06-19" @default.
• W3034971189 creator A5027509402 @default.
• W3034971189 creator A5040672078 @default.
• W3034971189 creator A5049187296 @default.
• W3034971189 date "2020-06-10" @default.
• W3034971189 modified "2023-09-25" @default.
• W3034971189 title "Inherited Bleeding Disorders in Pediatric Patients; experience of the national referral center in Iraq" @default.
• W3034971189 cites W125515877 @default.
• W3034971189 cites W1496174784 @default.
• W3034971189 cites W1925532765 @default.
• W3034971189 cites W1990942416 @default.
• W3034971189 cites W1998339158 @default.
• W3034971189 cites W2037919104 @default.
• W3034971189 cites W2088562483 @default.
• W3034971189 cites W2114395769 @default.
• W3034971189 cites W2154795251 @default.
• W3034971189 cites W2809724049 @default.
• W3034971189 cites W3122535043 @default.
• W3034971189 doi "https://doi.org/10.1007/s12288-020-01306-8" @default.
• W3034971189 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7900310" @default.
• W3034971189 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33707841" @default.
• W3034971189 hasPublicationYear "2020" @default.
• W3034971189 type Work @default.
• W3034971189 sameAs 3034971189 @default.
• W3034971189 citedByCount "0" @default.
• W3034971189 crossrefType "journal-article" @default.
• W3034971189 hasAuthorship W3034971189A5027509402 @default.
• W3034971189 hasAuthorship W3034971189A5040672078 @default.
• W3034971189 hasAuthorship W3034971189A5049187296 @default.
• W3034971189 hasBestOaLocation W30349711892 @default.
• W3034971189 hasConcept C126322002 @default.
• W3034971189 hasConcept C187212893 @default.
• W3034971189 hasConcept C194409129 @default.
• W3034971189 hasConcept C2778780528 @default.
• W3034971189 hasConcept C2779394231 @default.
• W3034971189 hasConcept C2781179581 @default.
• W3034971189 hasConcept C2908742493 @default.
• W3034971189 hasConcept C2993802102 @default.
• W3034971189 hasConcept C71924100 @default.
• W3034971189 hasConcept C89560881 @default.
• W3034971189 hasConcept C90924648 @default.
• W3034971189 hasConceptScore W3034971189C126322002 @default.
• W3034971189 hasConceptScore W3034971189C187212893 @default.
• W3034971189 hasConceptScore W3034971189C194409129 @default.
• W3034971189 hasConceptScore W3034971189C2778780528 @default.
• W3034971189 hasConceptScore W3034971189C2779394231 @default.
• W3034971189 hasConceptScore W3034971189C2781179581 @default.
• W3034971189 hasConceptScore W3034971189C2908742493 @default.
• W3034971189 hasConceptScore W3034971189C2993802102 @default.
• W3034971189 hasConceptScore W3034971189C71924100 @default.
• W3034971189 hasConceptScore W3034971189C89560881 @default.
• W3034971189 hasConceptScore W3034971189C90924648 @default.
• W3034971189 hasIssue "1" @default.
• W3034971189 hasLocation W30349711891 @default.
• W3034971189 hasLocation W30349711892 @default.
• W3034971189 hasLocation W30349711893 @default.
• W3034971189 hasOpenAccess W3034971189 @default.
• W3034971189 hasPrimaryLocation W30349711891 @default.
• W3034971189 hasRelatedWork W1987032672 @default.
• W3034971189 hasRelatedWork W2027233997 @default.
• W3034971189 hasRelatedWork W2047182202 @default.
• W3034971189 hasRelatedWork W2051734978 @default.
• W3034971189 hasRelatedWork W2081737706 @default.
• W3034971189 hasRelatedWork W2117390047 @default.
• W3034971189 hasRelatedWork W2280697081 @default.
• W3034971189 hasRelatedWork W2335070244 @default.
• W3034971189 hasRelatedWork W2418729721 @default.
• W3034971189 hasRelatedWork W3117585051 @default.
• W3034971189 hasVolume "37" @default.
• W3034971189 isParatext "false" @default.
• W3034971189 isRetracted "false" @default.
• W3034971189 magId "3034971189" @default.
• W3034971189 workType "article" @default.