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- W3035013740 abstract "Control of protein synthesis (mRNA translation) is essential for proper brain development and function. Perturbations to the mechanisms governing mRNA translation have repeatedly been shown to constitute a neurodegenerative, neuropsychiatric, and neurodevelopmental disorder risk factor. Developing effective therapeutics for brain disorders will require a better understanding of the molecular mechanisms underlying the control of protein synthesis in brain function. Studies using transgenic animal models have been invaluable towards this end, providing exciting new insights into the genetic basis of brain disorders with hopeful prospects for new and effective treatment options." @default.
- W3035013740 created "2020-06-19" @default.
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- W3035013740 date "2020-12-01" @default.
- W3035013740 modified "2023-10-18" @default.
- W3035013740 title "Dysregulated translational control in brain disorders: from genes to behavior" @default.
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- W3035013740 doi "https://doi.org/10.1016/j.gde.2020.05.005" @default.
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