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- W3035089933 startingPage "185" @default.
- W3035089933 abstract "Abstract Dendritic spines are tiny membrane specialization forming the postsynaptic part of most excitatory synapses. They have been suggested to play a crucial role in regulating synaptic transmission during development and in adult learning processes. Changes in their number, size, and shape are correlated with processes of structural synaptic plasticity and learning and memory and also with neurodegenerative diseases, when spines are lost. Thus, their alterations can correlate with neuronal homeostasis, but also with dysfunction in several neurological disorders characterized by cognitive impairment. Therefore, it is important to understand how different stages in the life of a dendritic spine, including formation, maturation, and plasticity, are strictly regulated. In this context, brain-derived neurotrophic factor (BDNF), belonging to the NGF-neurotrophin family, is among the most intensively investigated molecule. This review would like to report the current knowledge regarding the role of BDNF in regulating dendritic spine number, structure, and plasticity concentrating especially on its signaling via its two often functionally antagonistic receptors, TrkB and p75 NTR . In addition, we point out a series of open points in which, while the role of BDNF signaling is extremely likely conclusive, evidence is still missing." @default.
- W3035089933 created "2020-06-19" @default.
- W3035089933 creator A5071260270 @default.
- W3035089933 creator A5080547447 @default.
- W3035089933 creator A5080722888 @default.
- W3035089933 date "2020-06-14" @default.
- W3035089933 modified "2023-10-13" @default.
- W3035089933 title "BDNF signaling during the lifetime of dendritic spines" @default.
- W3035089933 cites W124833595 @default.
- W3035089933 cites W1440335865 @default.
- W3035089933 cites W1487695731 @default.
- W3035089933 cites W1499836217 @default.
- W3035089933 cites W1500274950 @default.
- W3035089933 cites W151176851 @default.
- W3035089933 cites W1552458995 @default.
- W3035089933 cites W1553814286 @default.
- W3035089933 cites W1572640432 @default.
- W3035089933 cites W1595455317 @default.
- W3035089933 cites W1595936241 @default.
- W3035089933 cites W1602778375 @default.
- W3035089933 cites W1648996761 @default.
- W3035089933 cites W1899761214 @default.
- W3035089933 cites W1966155655 @default.
- W3035089933 cites W1967625322 @default.
- W3035089933 cites W1969171489 @default.
- W3035089933 cites W1970151100 @default.
- W3035089933 cites W1973159860 @default.
- W3035089933 cites W1973506089 @default.
- W3035089933 cites W1973800582 @default.
- W3035089933 cites W1974476511 @default.
- W3035089933 cites W1974971758 @default.
- W3035089933 cites W1978611788 @default.
- W3035089933 cites W1978668014 @default.
- W3035089933 cites W1979019425 @default.
- W3035089933 cites W1979233894 @default.
- W3035089933 cites W1979496428 @default.
- W3035089933 cites W1979794821 @default.
- W3035089933 cites W1980452424 @default.
- W3035089933 cites W1983080743 @default.
- W3035089933 cites W1983509957 @default.
- W3035089933 cites W1983553517 @default.
- W3035089933 cites W1983951432 @default.
- W3035089933 cites W1984726790 @default.
- W3035089933 cites W1985044857 @default.
- W3035089933 cites W1986246328 @default.
- W3035089933 cites W1988011192 @default.
- W3035089933 cites W1989976072 @default.
- W3035089933 cites W1990479642 @default.
- W3035089933 cites W1990811550 @default.
- W3035089933 cites W1991770248 @default.
- W3035089933 cites W1995290481 @default.
- W3035089933 cites W1995412725 @default.
- W3035089933 cites W1996893328 @default.
- W3035089933 cites W1997123576 @default.
- W3035089933 cites W1998261300 @default.
- W3035089933 cites W2001528712 @default.
- W3035089933 cites W2003665687 @default.
- W3035089933 cites W2004107819 @default.
- W3035089933 cites W2004305267 @default.
- W3035089933 cites W2005254595 @default.
- W3035089933 cites W2006374396 @default.
- W3035089933 cites W2006733352 @default.
- W3035089933 cites W2017613746 @default.
- W3035089933 cites W2018460010 @default.
- W3035089933 cites W2018956292 @default.
- W3035089933 cites W2019124038 @default.
- W3035089933 cites W2022731311 @default.
- W3035089933 cites W2022777861 @default.
- W3035089933 cites W2024034126 @default.
- W3035089933 cites W2024115934 @default.
- W3035089933 cites W2024694517 @default.
- W3035089933 cites W2026010744 @default.
- W3035089933 cites W2027267723 @default.
- W3035089933 cites W2029815010 @default.
- W3035089933 cites W2036966153 @default.
- W3035089933 cites W2037462628 @default.
- W3035089933 cites W2037708431 @default.
- W3035089933 cites W2038839265 @default.
- W3035089933 cites W2039255376 @default.
- W3035089933 cites W2039969351 @default.
- W3035089933 cites W2041963605 @default.
- W3035089933 cites W2044295155 @default.
- W3035089933 cites W2046033738 @default.
- W3035089933 cites W2046866871 @default.
- W3035089933 cites W2047731623 @default.
- W3035089933 cites W2048483121 @default.
- W3035089933 cites W2049692154 @default.
- W3035089933 cites W2050042714 @default.
- W3035089933 cites W2051556001 @default.
- W3035089933 cites W2052426068 @default.
- W3035089933 cites W2053457664 @default.
- W3035089933 cites W2055583081 @default.
- W3035089933 cites W2055667548 @default.
- W3035089933 cites W2055804501 @default.
- W3035089933 cites W2055824658 @default.
- W3035089933 cites W2060411448 @default.
- W3035089933 cites W2063252423 @default.
- W3035089933 cites W2063314066 @default.