Matches in SemOpenAlex for { <https://semopenalex.org/work/W3035134076> ?p ?o ?g. }
- W3035134076 endingPage "109183" @default.
- W3035134076 startingPage "109183" @default.
- W3035134076 abstract "The present study analyzed whether melatonin could mediate the expression of VEGF, IL-6 and TNF-α, as well as the apoptotic index in rats with diabetic retinopathy. Fifty Wistar albino rats were divided into the following groups: GC: rats without induction of diabetes by streptozotocin; GD: rats induced to diabetes by streptozotocin and treated with placebo; GDM: rats induced to diabetes by streptozotocin and after confirmation treated with melatonin at a dose of 10 mg/kg for 20 days; GDMS: rats induced to diabetes by streptozotocin and treated simultaneously with melatonin at a dosage of 10 mg/kg for 20 days; GDI: rats induced to diabetes by streptozotocin and after confirmation treated with insulin for 20 days. Diabetes was induced by intraperitoneal injections of streptozotocin (60 mg/kg), and insulin (5 U/day) was administered subcutaneously. For apoptosis TUNEL was used, while for the analysis of VEGF, IL-6 and TNF-α. The results showed that the groups that were treated with melatonin decreased the expression of cytokines and VEGF, in addition to apoptosis. Thus, it is concluded that melatonin can regulate the expression of these factors by improving the condition of the retina in diabetic retinopathy." @default.
- W3035134076 created "2020-06-19" @default.
- W3035134076 creator A5016431190 @default.
- W3035134076 creator A5016509484 @default.
- W3035134076 creator A5026850359 @default.
- W3035134076 creator A5036904051 @default.
- W3035134076 creator A5044659242 @default.
- W3035134076 creator A5056102383 @default.
- W3035134076 creator A5060609948 @default.
- W3035134076 creator A5075703602 @default.
- W3035134076 creator A5076452542 @default.
- W3035134076 date "2020-08-01" @default.
- W3035134076 modified "2023-10-16" @default.
- W3035134076 title "Melatonin regulates the expression of inflammatory cytokines, VEGF and apoptosis in diabetic retinopathy in rats" @default.
- W3035134076 cites W1508167383 @default.
- W3035134076 cites W1728276264 @default.
- W3035134076 cites W1923288651 @default.
- W3035134076 cites W1965054947 @default.
- W3035134076 cites W1973199799 @default.
- W3035134076 cites W1976353252 @default.
- W3035134076 cites W1976474010 @default.
- W3035134076 cites W1977225442 @default.
- W3035134076 cites W1980837668 @default.
- W3035134076 cites W1981495544 @default.
- W3035134076 cites W1982947572 @default.
- W3035134076 cites W1983921503 @default.
- W3035134076 cites W1984979932 @default.
- W3035134076 cites W1991293065 @default.
- W3035134076 cites W1991945233 @default.
- W3035134076 cites W1996032049 @default.
- W3035134076 cites W2014840457 @default.
- W3035134076 cites W2016462237 @default.
- W3035134076 cites W2025419894 @default.
- W3035134076 cites W2025517512 @default.
- W3035134076 cites W2032094259 @default.
- W3035134076 cites W2032425910 @default.
- W3035134076 cites W2032561678 @default.
- W3035134076 cites W2039527984 @default.
- W3035134076 cites W2047640394 @default.
- W3035134076 cites W2048428155 @default.
- W3035134076 cites W2049884331 @default.
- W3035134076 cites W2057683168 @default.
- W3035134076 cites W2061975025 @default.
- W3035134076 cites W2062109170 @default.
- W3035134076 cites W2063844610 @default.
- W3035134076 cites W2064711537 @default.
- W3035134076 cites W2072622931 @default.
- W3035134076 cites W2078616098 @default.
- W3035134076 cites W2083158975 @default.
- W3035134076 cites W2090634242 @default.
- W3035134076 cites W2092579092 @default.
- W3035134076 cites W2110252008 @default.
- W3035134076 cites W2123215356 @default.
- W3035134076 cites W2123350325 @default.
- W3035134076 cites W2128766854 @default.
- W3035134076 cites W2131731266 @default.
- W3035134076 cites W2132949972 @default.
- W3035134076 cites W2137786107 @default.
- W3035134076 cites W2143596271 @default.
- W3035134076 cites W2149868030 @default.
- W3035134076 cites W2156068394 @default.
- W3035134076 cites W2163778916 @default.
- W3035134076 cites W2168572849 @default.
- W3035134076 cites W2407351686 @default.
- W3035134076 cites W2898113033 @default.
- W3035134076 cites W4231050902 @default.
- W3035134076 cites W4295065557 @default.
- W3035134076 cites W1838723084 @default.
- W3035134076 doi "https://doi.org/10.1016/j.cbi.2020.109183" @default.
- W3035134076 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32554039" @default.
- W3035134076 hasPublicationYear "2020" @default.
- W3035134076 type Work @default.
- W3035134076 sameAs 3035134076 @default.
- W3035134076 citedByCount "18" @default.
- W3035134076 countsByYear W30351340762020 @default.
- W3035134076 countsByYear W30351340762021 @default.
- W3035134076 countsByYear W30351340762022 @default.
- W3035134076 countsByYear W30351340762023 @default.
- W3035134076 crossrefType "journal-article" @default.
- W3035134076 hasAuthorship W3035134076A5016431190 @default.
- W3035134076 hasAuthorship W3035134076A5016509484 @default.
- W3035134076 hasAuthorship W3035134076A5026850359 @default.
- W3035134076 hasAuthorship W3035134076A5036904051 @default.
- W3035134076 hasAuthorship W3035134076A5044659242 @default.
- W3035134076 hasAuthorship W3035134076A5056102383 @default.
- W3035134076 hasAuthorship W3035134076A5060609948 @default.
- W3035134076 hasAuthorship W3035134076A5075703602 @default.
- W3035134076 hasAuthorship W3035134076A5076452542 @default.
- W3035134076 hasBestOaLocation W30351340761 @default.
- W3035134076 hasConcept C126322002 @default.
- W3035134076 hasConcept C134018914 @default.
- W3035134076 hasConcept C164027704 @default.
- W3035134076 hasConcept C167734588 @default.
- W3035134076 hasConcept C190283241 @default.
- W3035134076 hasConcept C196795494 @default.
- W3035134076 hasConcept C204232928 @default.
- W3035134076 hasConcept C2776914184 @default.
- W3035134076 hasConcept C2777025900 @default.