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• W3035149656 abstract "Hypersonins A–D (1–4), four 1,2-seco-homoadamantane type polycyclic polyprenylated acylphloroglucinols (PPAPs) possessing a new bicyclo[4.3.1]decane-3-methoxycarbonyl architecture, were obtained from Hypericum wilsonii. The structures of hypersonins A–D were identified by spectroscopic data, electronic circular dichroism comparison, and X-ray crystallographic data. Hypersonins A–D are the first seco-homoadamantane-type PPAPs with cleavage at the C-1–C-2 bond. Hypersonin A (1) showed moderate inhibitory activity to anti-CD3/anti-CD28 monoclonal antibody-induced proliferation of murine splenocytes, with an IC50 value of 8.3 ± 0.2 μM." @default.
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• W3035149656 date "2020-06-16" @default.
• W3035149656 modified "2023-10-16" @default.
• W3035149656 title "Hypersonins A–D, Polycyclic Polyprenylated Acylphloroglucinols with a 1,2-<i>seco</i>-Homoadamantane Architecture from <i>Hypericum wilsonii</i>" @default.
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• W3035149656 doi "https://doi.org/10.1021/acs.jnatprod.9b01187" @default.
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