FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3035157026> ?p ?o ?g. }

• W3035157026 abstract "Neutropenic enterocolitis (NE) also known as typhlitis is a serious condition that has been described in immunosuppressed hosts including patients with leukemia, HIV and in patients on chemotherapy. We present the first case of female on sulfasalazine for psoriatic arthritis, otherwise healthy, who was diagnosed with NE involving the cecum and rectum. This adds up to the cases of NE diagnosed in nononcologic conditions. A 65-year-old female with a history of psoriatic arthritis on sulfasalazine, presented to the emergency department (ED) after an episode of syncope. She was complaining of a fever and mild generalized abdominal pain. Physical exam was remarkable for peri-umbilical tenderness. Severe neutropenia and acute kidney injury were found on blood work. CT scan of the abdomen showed evidence of colitis, involving the cecum, ascending colon and rectum, which in light of neutropenia was consistent with NE. Clostridium difficile colitis was ruled out. Intravenous fluids and broad-spectrum antibiotics were initiated, and sulfasalazine was discontinued. The patient was subsequently afebrile and was out of neutropenia by day 3 without the need for granulocyte-macrophage colony-stimulating factor (GM-CSF). By day 5, the patient was pain free and was discharged. Even though NE is primarily described in the setting of malignancies and chemotherapy, one should keep in mind that this entity can occur in people on any immunosuppressive therapy. Early discontinuation of sulfasalazine and conservative management were essential in the treatment of NE in this case. Whether neutropenia precipitates colitis or the latter causes agranulocytosis by bone marrow suppression through cytokines remains to be proved. The diagnosis of medication-related adverse reactions remains a big challenge for clinicians and therefore requires a high index of suspicion. Resolution of the symptoms can simply occur with the discontinuation of the offending drug and often does not require extensive workup or treatments that might cause harm to the patient's health." @default.
• W3035157026 created "2020-06-19" @default.
• W3035157026 creator A5000904438 @default.
• W3035157026 creator A5012396780 @default.
• W3035157026 creator A5025023782 @default.
• W3035157026 creator A5070223324 @default.
• W3035157026 creator A5080835956 @default.
• W3035157026 date "2020-06-12" @default.
• W3035157026 modified "2023-09-26" @default.
• W3035157026 title "Neutropenic Enterocolitis Secondary to Sulfasalazine in a Woman With Psoriatic Arthritis" @default.
• W3035157026 cites W189427349 @default.
• W3035157026 cites W1971466810 @default.
• W3035157026 cites W1985386247 @default.
• W3035157026 cites W1985616114 @default.
• W3035157026 cites W1992955478 @default.
• W3035157026 cites W2017739211 @default.
• W3035157026 cites W2036021766 @default.
• W3035157026 cites W2050077474 @default.
• W3035157026 cites W2119505130 @default.
• W3035157026 cites W2123638354 @default.
• W3035157026 cites W2132431829 @default.
• W3035157026 cites W2137077870 @default.
• W3035157026 cites W2144168299 @default.
• W3035157026 cites W2149134901 @default.
• W3035157026 cites W97893390 @default.
• W3035157026 doi "https://doi.org/10.7759/cureus.8576" @default.
• W3035157026 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7358926" @default.
• W3035157026 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32670712" @default.
• W3035157026 hasPublicationYear "2020" @default.
• W3035157026 type Work @default.
• W3035157026 sameAs 3035157026 @default.
• W3035157026 citedByCount "1" @default.
• W3035157026 countsByYear W30351570262020 @default.
• W3035157026 crossrefType "journal-article" @default.
• W3035157026 hasAuthorship W3035157026A5000904438 @default.
• W3035157026 hasAuthorship W3035157026A5012396780 @default.
• W3035157026 hasAuthorship W3035157026A5025023782 @default.
• W3035157026 hasAuthorship W3035157026A5070223324 @default.
• W3035157026 hasAuthorship W3035157026A5080835956 @default.
• W3035157026 hasBestOaLocation W30351570261 @default.
• W3035157026 hasConcept C126322002 @default.
• W3035157026 hasConcept C141071460 @default.
• W3035157026 hasConcept C2775862500 @default.
• W3035157026 hasConcept C2776258884 @default.
• W3035157026 hasConcept C2776260265 @default.
• W3035157026 hasConcept C2776694085 @default.
• W3035157026 hasConcept C2777063308 @default.
• W3035157026 hasConcept C2777077863 @default.
• W3035157026 hasConcept C2778715236 @default.
• W3035157026 hasConcept C2778850193 @default.
• W3035157026 hasConcept C2779134260 @default.
• W3035157026 hasConcept C2779383735 @default.
• W3035157026 hasConcept C2780479503 @default.
• W3035157026 hasConcept C2780955771 @default.
• W3035157026 hasConcept C2909592510 @default.
• W3035157026 hasConcept C2994496256 @default.
• W3035157026 hasConcept C501593827 @default.
• W3035157026 hasConcept C71924100 @default.
• W3035157026 hasConcept C86803240 @default.
• W3035157026 hasConcept C89423630 @default.
• W3035157026 hasConcept C90924648 @default.
• W3035157026 hasConceptScore W3035157026C126322002 @default.
• W3035157026 hasConceptScore W3035157026C141071460 @default.
• W3035157026 hasConceptScore W3035157026C2775862500 @default.
• W3035157026 hasConceptScore W3035157026C2776258884 @default.
• W3035157026 hasConceptScore W3035157026C2776260265 @default.
• W3035157026 hasConceptScore W3035157026C2776694085 @default.
• W3035157026 hasConceptScore W3035157026C2777063308 @default.
• W3035157026 hasConceptScore W3035157026C2777077863 @default.
• W3035157026 hasConceptScore W3035157026C2778715236 @default.
• W3035157026 hasConceptScore W3035157026C2778850193 @default.
• W3035157026 hasConceptScore W3035157026C2779134260 @default.
• W3035157026 hasConceptScore W3035157026C2779383735 @default.
• W3035157026 hasConceptScore W3035157026C2780479503 @default.
• W3035157026 hasConceptScore W3035157026C2780955771 @default.
• W3035157026 hasConceptScore W3035157026C2909592510 @default.
• W3035157026 hasConceptScore W3035157026C2994496256 @default.
• W3035157026 hasConceptScore W3035157026C501593827 @default.
• W3035157026 hasConceptScore W3035157026C71924100 @default.
• W3035157026 hasConceptScore W3035157026C86803240 @default.
• W3035157026 hasConceptScore W3035157026C89423630 @default.
• W3035157026 hasConceptScore W3035157026C90924648 @default.
• W3035157026 hasLocation W30351570261 @default.
• W3035157026 hasLocation W30351570262 @default.
• W3035157026 hasLocation W30351570263 @default.
• W3035157026 hasLocation W30351570264 @default.
• W3035157026 hasOpenAccess W3035157026 @default.
• W3035157026 hasPrimaryLocation W30351570261 @default.
• W3035157026 hasRelatedWork W2004482386 @default.
• W3035157026 hasRelatedWork W2031497779 @default.
• W3035157026 hasRelatedWork W2118211258 @default.
• W3035157026 hasRelatedWork W2136975042 @default.
• W3035157026 hasRelatedWork W2167708522 @default.
• W3035157026 hasRelatedWork W2540799500 @default.
• W3035157026 hasRelatedWork W3008389790 @default.
• W3035157026 hasRelatedWork W3035157026 @default.
• W3035157026 hasRelatedWork W3047145206 @default.
• W3035157026 hasRelatedWork W4233466023 @default.
• W3035157026 isParatext "false" @default.
• W3035157026 isRetracted "false" @default.

• next