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- W3035189969 abstract "A 32-year-old male presented for initial evaluation of alopecia on the frontal scalp of eight months duration. On initial clinical examination, he was found to have a 7.0cm x 1.2cm sclerotic plaque on the paramedian forehead extending to the scalp with associated alopecia. No ocular, neurological, or odontostomatologic complications were identified. A 4mm punch biopsy from the frontal scalp demonstrated marked follicular dropout with absent sebaceous glands and presence of perifollicular and perivascular lymphocytic inflammation. There was vacuolar alteration and clefting along the basement membrane with necrotic keratinocytes and evidence of dermal fibrosis. These findings were consistent with a diagnosis of early, inflammatory linear morphea. On dermoscopy, there was perifollicular scale scattered with loss of follicular openings on a pink-white surface. Pinpoint follicular black dots, broken hairs, several short vellus hairs and pili torti were appreciated. Minoxidil was initially trialed without resulting hair regrowth. The patient was subsequently treated with topical calcitriol, desonide cream and fluocinonide cream for one year. Thereafter, he exclusively used pimecrolimus cream twice daily with regrowth of hair noted on clinical and dermoscopic evaluation. Although linear morphea may result in scarring alopecia, our patient remarkably experienced hair regrowth throughout his treatment. Our report demonstrates the importance of dermoscopy in assisting diagnosis of linear morphea and highlights the utility of dermoscopy in monitoring progression or improvement of disease, as evidenced by the short vellus hairs on dermoscopy, as well as a tool to monitor progression or resolution of disease, as evidenced by short vellus hairs on dermoscopy." @default.
- W3035189969 created "2020-06-19" @default.
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- W3035189969 date "2020-07-01" @default.
- W3035189969 modified "2023-10-14" @default.
- W3035189969 title "083 Linear morphea with evidence of hair regrowth" @default.
- W3035189969 doi "https://doi.org/10.1016/j.jid.2020.03.085" @default.
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