FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3035235510> ?p ?o ?g. }

• W3035235510 endingPage "574" @default.
• W3035235510 startingPage "567" @default.
• W3035235510 abstract "The incidence of inflammatory bowel disease (IBD) in juvenile idiopathic arthritis (JIA) is higher than in the general pediatric population. However, reports of IBD in the systemic JIA (sJIA) subtype are limited. We sought to characterize sJIA patients diagnosed with IBD and to identify potential contributing risk factors.Using an internationally distributed survey, we identified 16 patients with sJIA who were subsequently diagnosed with IBD (sJIA-IBD cohort). Five hundred twenty-two sJIA patients without IBD were identified from the CARRA Legacy Registry and served as the sJIA-only cohort for comparison. Differences in demographic, clinical characteristics, and therapy were assessed using chi-square test, Fisher exact test, t-test, and univariate and multivariate logistic regression, as appropriate.Of the patients with sJIA-IBD, 75% had a persistent sJIA course and 25% had a history of macrophage activation syndrome. sJIA-IBD subjects were older at sJIA diagnosis, more often non-White, had a higher rate of IBD family history, and were more frequently treated with etanercept or canakinumab compared to sJIA-only subjects. Sixty-nine percent of sJIA-IBD patients successfully discontinued sJIA medications following IBD diagnosis, and sJIA symptoms resolved in 9 of 12 patients treated with tumor necrosis factor-α (TNF-α) inhibitors.IBD in the setting of sJIA is a rare occurrence. The favorable response of sJIA symptoms to therapeutic TNF-α inhibition suggests that the sJIA-IBD cohort may represent a mechanistically distinct sJIA subgroup. Our study highlights the importance of maintaining a high level of suspicion for IBD when gastrointestinal involvement occurs in patients with sJIA and the likely broad benefit of TNF-α inhibition in those cases." @default.
• W3035235510 created "2020-06-19" @default.
• W3035235510 creator A5001813193 @default.
• W3035235510 creator A5011075296 @default.
• W3035235510 creator A5013295999 @default.
• W3035235510 creator A5013648604 @default.
• W3035235510 creator A5016731880 @default.
• W3035235510 creator A5017022896 @default.
• W3035235510 creator A5017214251 @default.
• W3035235510 creator A5023498614 @default.
• W3035235510 creator A5039644486 @default.
• W3035235510 creator A5047262522 @default.
• W3035235510 creator A5054340835 @default.
• W3035235510 creator A5060272554 @default.
• W3035235510 creator A5069613217 @default.
• W3035235510 creator A5073214698 @default.
• W3035235510 creator A5078990535 @default.
• W3035235510 creator A5079738832 @default.
• W3035235510 creator A5085543847 @default.
• W3035235510 creator A5089162243 @default.
• W3035235510 creator A5090438118 @default.
• W3035235510 date "2020-06-15" @default.
• W3035235510 modified "2023-10-01" @default.
• W3035235510 title "Inflammatory Bowel Disease in Children With Systemic Juvenile Idiopathic Arthritis" @default.
• W3035235510 cites W1014257459 @default.
• W3035235510 cites W1581139251 @default.
• W3035235510 cites W1806733851 @default.
• W3035235510 cites W1915598702 @default.
• W3035235510 cites W1974138441 @default.
• W3035235510 cites W1988825081 @default.
• W3035235510 cites W1993243556 @default.
• W3035235510 cites W1996697769 @default.
• W3035235510 cites W2010387075 @default.
• W3035235510 cites W2017213437 @default.
• W3035235510 cites W2024346860 @default.
• W3035235510 cites W2038021373 @default.
• W3035235510 cites W2045113701 @default.
• W3035235510 cites W2052118031 @default.
• W3035235510 cites W2064500584 @default.
• W3035235510 cites W2065850695 @default.
• W3035235510 cites W2070086022 @default.
• W3035235510 cites W2077228969 @default.
• W3035235510 cites W2087769239 @default.
• W3035235510 cites W2106696914 @default.
• W3035235510 cites W2106779017 @default.
• W3035235510 cites W2132133634 @default.
• W3035235510 cites W2143625465 @default.
• W3035235510 cites W2147961647 @default.
• W3035235510 cites W2149253120 @default.
• W3035235510 cites W2166106092 @default.
• W3035235510 cites W2221264044 @default.
• W3035235510 cites W2269280129 @default.
• W3035235510 cites W2339545100 @default.
• W3035235510 cites W2404397294 @default.
• W3035235510 cites W2405101776 @default.
• W3035235510 cites W2421298451 @default.
• W3035235510 cites W2444247510 @default.
• W3035235510 cites W2471477713 @default.
• W3035235510 cites W2481838947 @default.
• W3035235510 cites W2560661426 @default.
• W3035235510 cites W2564035682 @default.
• W3035235510 cites W2597068472 @default.
• W3035235510 cites W2607459568 @default.
• W3035235510 cites W2766046358 @default.
• W3035235510 cites W2810862053 @default.
• W3035235510 cites W2902646333 @default.
• W3035235510 cites W2922158322 @default.
• W3035235510 cites W2954049110 @default.
• W3035235510 cites W2954986885 @default.
• W3035235510 cites W2964381395 @default.
• W3035235510 cites W2973690082 @default.
• W3035235510 cites W2977581039 @default.
• W3035235510 cites W3013698693 @default.
• W3035235510 cites W33672687 @default.
• W3035235510 doi "https://doi.org/10.3899/jrheum.200230" @default.
• W3035235510 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7736056" @default.
• W3035235510 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32541073" @default.
• W3035235510 hasPublicationYear "2020" @default.
• W3035235510 type Work @default.
• W3035235510 sameAs 3035235510 @default.
• W3035235510 citedByCount "8" @default.
• W3035235510 countsByYear W30352355102021 @default.
• W3035235510 countsByYear W30352355102022 @default.
• W3035235510 countsByYear W30352355102023 @default.
• W3035235510 crossrefType "journal-article" @default.
• W3035235510 hasAuthorship W3035235510A5001813193 @default.
• W3035235510 hasAuthorship W3035235510A5011075296 @default.
• W3035235510 hasAuthorship W3035235510A5013295999 @default.
• W3035235510 hasAuthorship W3035235510A5013648604 @default.
• W3035235510 hasAuthorship W3035235510A5016731880 @default.
• W3035235510 hasAuthorship W3035235510A5017022896 @default.
• W3035235510 hasAuthorship W3035235510A5017214251 @default.
• W3035235510 hasAuthorship W3035235510A5023498614 @default.
• W3035235510 hasAuthorship W3035235510A5039644486 @default.
• W3035235510 hasAuthorship W3035235510A5047262522 @default.
• W3035235510 hasAuthorship W3035235510A5054340835 @default.
• W3035235510 hasAuthorship W3035235510A5060272554 @default.
• W3035235510 hasAuthorship W3035235510A5069613217 @default.

• next