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• W3035324935 abstract "Polycystic ovary syndrome (PCOS), a disease that usually emerges during adolescence, is characterized by hormonal imbalance and ovarian dysfunction. The prevalence can vary between 5.6% to 21.3% in women and 6% in adolescent girls. This discrepancy is related to the population studied and the diagnostic criteria used. The underlying pathophysiology of PCOS is not fully understood, but it can lead to a number of co-morbidities, including hypertension, diabetes, dyslipidemia and, also, mental health disorders. Clinical and preclinical data indicate neuroendocrine involvement with dysfunction in GABA signaling and neuronal androgen receptors that might reduce hypothalamic sensitivity and lead to an impairment of estradiol and progesterone feedback. Based on these assumptions, the aims of this paper are to review the association of PCOS and psychotic disorders in order to address the burden of women comorbid for both conditions." @default.
• W3035324935 created "2020-06-19" @default.
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• W3035324935 date "2020-06-10" @default.
• W3035324935 modified "2023-09-29" @default.
• W3035324935 title "Polycystic Ovary Syndrome and Psychotic Disorder" @default.
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• W3035324935 doi "https://doi.org/10.3389/fpsyt.2020.00543" @default.
• W3035324935 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7297942" @default.
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• W3035324935 hasPublicationYear "2020" @default.
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