FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3035394842> ?p ?o ?g. }

• W3035394842 abstract "Abstract Objective Vitamin D (vitD) deficiency is a global childhood health problem. Food fortification is a promising strategy to curb vitD deficiency. We aimed to assess the effectiveness of utilizing vitD fortification in staple foods to improve 25hydroxyvitamin D (25(OH)D) concentration and to reduce the prevalence of vitD deficiency among healthy children. Methods We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) evaluating the use of vitD fortified food products compared to no fortification among healthy children aged 1–18 years old. We searched Medline, Embase, Global Health, and Cochrane (CENTRAL) databases from database inception until May 2019. Independently, six reviewers in pairs screened titles and abstracts, assessed the full text for eligibility, and performed data extraction and quality assessment. The primary outcome is the impact of fortification on 25(OH)D concentration. The secondary outcomes included the impact of fortification on the prevalence of vitD deficiency, school performance, cognitive function, school absences, infection rate, hospital admission length, and compliance with fortified food product consumption. Results We identified 2229 articles. After assessing eligibility, 20 RCTs met the inclusion criteria. The eligible RCTs assessed the fortification of milk, cereal, juice, bread, yogurt, and cheese compared with no fortification. All RCTs, except for three, had a low risk of bias. Food fortification improved 25(OH)D concentration by a mean difference (MD) of 15.51 nmol/L (95% confidence interval (CI) 6.28, 24.74; I 2 = 99%), which resulted in a mean increase of 3 nmol/l for every 100 IU of vitD, when adjusted for baseline 25(OH)D concentration and country latitude. Additionally, the prevalence of vitD deficiency decreased by a risk ratio of 0.53 (95% CI 0.41, 0.69; I 2 = 95%), and cognitive function improved by a MD of 1.22 intelligence quotient (IQ) points (95% CI 0.65, 1.79; I 2 = 0%). The overall evidence quality was high. Conclusion VitD food fortification is an effective way to improve 25(OH)D concentration, prevent vitD deficiency, and improve IQ levels. Systematic review registration PROSPERO CRD42017057631" @default.
• W3035394842 created "2020-06-19" @default.
• W3035394842 creator A5041305114 @default.
• W3035394842 creator A5063611102 @default.
• W3035394842 creator A5064821710 @default.
• W3035394842 creator A5068853136 @default.
• W3035394842 creator A5077764736 @default.
• W3035394842 creator A5083659792 @default.
• W3035394842 creator A5090449510 @default.
• W3035394842 date "2020-06-16" @default.
• W3035394842 modified "2023-10-05" @default.
• W3035394842 title "The impact of vitamin D food fortification and health outcomes in children: a systematic review and meta-regression" @default.
• W3035394842 cites W1520658218 @default.
• W3035394842 cites W1808564681 @default.
• W3035394842 cites W1937687363 @default.
• W3035394842 cites W1959525883 @default.
• W3035394842 cites W1965503066 @default.
• W3035394842 cites W1966237429 @default.
• W3035394842 cites W1981680557 @default.
• W3035394842 cites W1992729000 @default.
• W3035394842 cites W1993465584 @default.
• W3035394842 cites W1993468246 @default.
• W3035394842 cites W1994006843 @default.
• W3035394842 cites W2000422963 @default.
• W3035394842 cites W2008870899 @default.
• W3035394842 cites W2009326492 @default.
• W3035394842 cites W2011842668 @default.
• W3035394842 cites W2021610751 @default.
• W3035394842 cites W2023523068 @default.
• W3035394842 cites W2025833127 @default.
• W3035394842 cites W2060133141 @default.
• W3035394842 cites W2078870948 @default.
• W3035394842 cites W2079897458 @default.
• W3035394842 cites W2082909923 @default.
• W3035394842 cites W2085005241 @default.
• W3035394842 cites W2090132603 @default.
• W3035394842 cites W2093043874 @default.
• W3035394842 cites W2093536899 @default.
• W3035394842 cites W2095535275 @default.
• W3035394842 cites W2096107473 @default.
• W3035394842 cites W2099665543 @default.
• W3035394842 cites W2106647095 @default.
• W3035394842 cites W2106739951 @default.
• W3035394842 cites W2107072401 @default.
• W3035394842 cites W2109346853 @default.
• W3035394842 cites W2110686615 @default.
• W3035394842 cites W2112381556 @default.
• W3035394842 cites W2120539364 @default.
• W3035394842 cites W2124070987 @default.
• W3035394842 cites W2124352477 @default.
• W3035394842 cites W2126617070 @default.
• W3035394842 cites W2129376095 @default.
• W3035394842 cites W2142544310 @default.
• W3035394842 cites W2144820143 @default.
• W3035394842 cites W2145653127 @default.
• W3035394842 cites W2152955619 @default.
• W3035394842 cites W2153059487 @default.
• W3035394842 cites W2158182511 @default.
• W3035394842 cites W2163716653 @default.
• W3035394842 cites W2170814415 @default.
• W3035394842 cites W2170835824 @default.
• W3035394842 cites W2170892587 @default.
• W3035394842 cites W2172022416 @default.
• W3035394842 cites W2209450960 @default.
• W3035394842 cites W2236292184 @default.
• W3035394842 cites W2286769842 @default.
• W3035394842 cites W2291359085 @default.
• W3035394842 cites W2462921763 @default.
• W3035394842 cites W2462935756 @default.
• W3035394842 cites W2467146467 @default.
• W3035394842 cites W2531285591 @default.
• W3035394842 cites W2570401349 @default.
• W3035394842 cites W2587803342 @default.
• W3035394842 cites W2588906490 @default.
• W3035394842 cites W2593147233 @default.
• W3035394842 cites W2612904435 @default.
• W3035394842 cites W2626080546 @default.
• W3035394842 cites W2716992514 @default.
• W3035394842 cites W2783879607 @default.
• W3035394842 cites W2792634664 @default.
• W3035394842 cites W2883053146 @default.
• W3035394842 cites W2884138665 @default.
• W3035394842 cites W2895389571 @default.
• W3035394842 cites W4214559180 @default.
• W3035394842 doi "https://doi.org/10.1186/s13643-020-01360-3" @default.
• W3035394842 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7298752" @default.
• W3035394842 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32546259" @default.
• W3035394842 hasPublicationYear "2020" @default.
• W3035394842 type Work @default.
• W3035394842 sameAs 3035394842 @default.
• W3035394842 citedByCount "19" @default.
• W3035394842 countsByYear W30353948422020 @default.
• W3035394842 countsByYear W30353948422021 @default.
• W3035394842 countsByYear W30353948422022 @default.
• W3035394842 countsByYear W30353948422023 @default.
• W3035394842 crossrefType "journal-article" @default.
• W3035394842 hasAuthorship W3035394842A5041305114 @default.
• W3035394842 hasAuthorship W3035394842A5063611102 @default.
• W3035394842 hasAuthorship W3035394842A5064821710 @default.
• W3035394842 hasAuthorship W3035394842A5068853136 @default.

• next