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• W3035444014 endingPage "105541" @default.
• W3035444014 startingPage "105541" @default.
• W3035444014 abstract "There has been a significant increased concern of the impact of the toxicity of multiple contaminants in the marine environment. Thus, this study was aimed at determining whether the interaction between nano-TiO2 and Cr(VI) would modulate their toxic effects with the marine crustacean, Artemia salina. Nano-TiO2 agglomerated in artificial sea water (ASW) and readily formed micron-sized particles that settled down in the medium. The addition of Cr(VI) to nano-TiO2 aggravated their agglomeration through sorption of Cr(VI) onto nano-TiO2. This was reflected by a decrease in the residual concentration of Cr in the suspension. Acute toxicity tests performed using pristine nano-TiO2 (0.25, 0.5, 1, 2, and 4 mg/L) and Cr(VI) (0.125, 0.25, 0.5, and 1 mg/L) displayed a concentration dependent rise in the mortality of Artemia salina. To examine the effects of mixtures of nano-TiO2 and Cr(VI) on Artemia salina, two groups of experiments were designed. The former group studied the toxic effect of nano-TiO2 (0.5, 1, 2, and 4 mg/L) with a fixed concentration (0.125 mg/L) of Cr(VI). While the latter group studied the toxicity of Cr(VI) (0.25, 0.5, and 1 mg/L) with a fixed concentration (0.25 mg/L) of nano-TiO2. The toxic effects of nano-TiO2 was not significantly reduced at a fixed concentration of Cr(VI) but in contrast, a significant reduction in the Cr(VI) toxicity by fixed concentration of nano-TiO2 was observed. Toxicity data was well supported by an independent action model that proved the mode of action between nano-TiO2 and Cr(VI) to be antagonistic. Furthermore, ROS generation and measurement of antioxidant enzyme activities were also in line with toxicity results. From this study, the modification of Cr(VI) toxicity at fixed concentration of nano-TiO2 could have a huge impact on the reduction in Cr(VI) toxicity across trophic levels." @default.
• W3035444014 created "2020-06-19" @default.
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• W3035444014 date "2020-08-01" @default.
• W3035444014 modified "2023-09-27" @default.
• W3035444014 title "Combined effects of nano-TiO2 and hexavalent chromium towards marine crustacean Artemia salina" @default.
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• W3035444014 doi "https://doi.org/10.1016/j.aquatox.2020.105541" @default.
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