Matches in SemOpenAlex for { <https://semopenalex.org/work/W3035449322> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W3035449322 endingPage "114" @default.
- W3035449322 startingPage "100" @default.
- W3035449322 abstract "Lipidomics covers analysis of all lipid species in an organism. Lipid metabolism is one of the key factors to understand cellular processes at molecular level. Lipidomics has been used to find diagnostic and prognostic biomarkers in clinical sample (plasma, serum, urine, tissue). Today mass spectroscopy based approach dominates lipidomics and several computational platforms have been developed to process raw mass spectra data. However, there is no routine procedure for data processing in lipidomics. In present work, two different bioinformatics platforms, which are MS-DIAL and MZmine2, was compared for lipidomics analysis of plasma sample. Peak detection, identification and quantification parameters were investigated to understand advantages and disadvantages. In peak detection process, it was observed that MZmine2 detected more peak than MS-DIAL at same threshold level. In identification process, Lipidmaps database was used for identification. MZmine2 identifies more lipid than MS-DIAL. Semi-quantification is very important to find differentially expressed lipid species and biomarkers in clinical studies. MS-DIAL and MZmine2 calculated normalized peak intensities and results were compared to understand reproducibility. Average relative standard deviation of all peaks was calculated and results showed that MS-DIAL gives more reproducible results than MZmine2. In conclusion, MZmine2 and MS-DIAL could be used in clinical lipidomics studies." @default.
- W3035449322 created "2020-06-19" @default.
- W3035449322 creator A5050417993 @default.
- W3035449322 date "2020-06-30" @default.
- W3035449322 modified "2023-09-26" @default.
- W3035449322 title "EVALUATION OF MS-DIAL AND MZMINE2 SOFTWARES FOR CLINICAL LIPIDOMICS ANALYSIS" @default.
- W3035449322 cites W1543068333 @default.
- W3035449322 cites W1971034551 @default.
- W3035449322 cites W1989299822 @default.
- W3035449322 cites W1998244941 @default.
- W3035449322 cites W2412021942 @default.
- W3035449322 cites W2527974276 @default.
- W3035449322 cites W2583344557 @default.
- W3035449322 cites W2597634187 @default.
- W3035449322 cites W2740955623 @default.
- W3035449322 cites W2752780351 @default.
- W3035449322 cites W2795506919 @default.
- W3035449322 cites W2800195412 @default.
- W3035449322 cites W2860719608 @default.
- W3035449322 cites W2883230647 @default.
- W3035449322 cites W2887496785 @default.
- W3035449322 cites W2972555219 @default.
- W3035449322 cites W2980820588 @default.
- W3035449322 cites W2981495005 @default.
- W3035449322 doi "https://doi.org/10.33769/aupse.673996" @default.
- W3035449322 hasPublicationYear "2020" @default.
- W3035449322 type Work @default.
- W3035449322 sameAs 3035449322 @default.
- W3035449322 citedByCount "1" @default.
- W3035449322 countsByYear W30354493222023 @default.
- W3035449322 crossrefType "journal-article" @default.
- W3035449322 hasAuthorship W3035449322A5050417993 @default.
- W3035449322 hasBestOaLocation W30354493221 @default.
- W3035449322 hasConcept C116834253 @default.
- W3035449322 hasConcept C162356407 @default.
- W3035449322 hasConcept C185592680 @default.
- W3035449322 hasConcept C21565614 @default.
- W3035449322 hasConcept C43617362 @default.
- W3035449322 hasConcept C58017582 @default.
- W3035449322 hasConcept C59822182 @default.
- W3035449322 hasConcept C60644358 @default.
- W3035449322 hasConcept C70721500 @default.
- W3035449322 hasConcept C86803240 @default.
- W3035449322 hasConceptScore W3035449322C116834253 @default.
- W3035449322 hasConceptScore W3035449322C162356407 @default.
- W3035449322 hasConceptScore W3035449322C185592680 @default.
- W3035449322 hasConceptScore W3035449322C21565614 @default.
- W3035449322 hasConceptScore W3035449322C43617362 @default.
- W3035449322 hasConceptScore W3035449322C58017582 @default.
- W3035449322 hasConceptScore W3035449322C59822182 @default.
- W3035449322 hasConceptScore W3035449322C60644358 @default.
- W3035449322 hasConceptScore W3035449322C70721500 @default.
- W3035449322 hasConceptScore W3035449322C86803240 @default.
- W3035449322 hasIssue "1" @default.
- W3035449322 hasLocation W30354493221 @default.
- W3035449322 hasLocation W30354493222 @default.
- W3035449322 hasOpenAccess W3035449322 @default.
- W3035449322 hasPrimaryLocation W30354493221 @default.
- W3035449322 hasRelatedWork W2003174742 @default.
- W3035449322 hasRelatedWork W2025819516 @default.
- W3035449322 hasRelatedWork W207791811 @default.
- W3035449322 hasRelatedWork W2208562635 @default.
- W3035449322 hasRelatedWork W2391375401 @default.
- W3035449322 hasRelatedWork W2511226988 @default.
- W3035449322 hasRelatedWork W2596100941 @default.
- W3035449322 hasRelatedWork W4255743975 @default.
- W3035449322 hasRelatedWork W4300980799 @default.
- W3035449322 hasRelatedWork W4310837363 @default.
- W3035449322 hasVolume "62" @default.
- W3035449322 isParatext "false" @default.
- W3035449322 isRetracted "false" @default.
- W3035449322 magId "3035449322" @default.
- W3035449322 workType "article" @default.