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- W3035774801 abstract "We have studied the effects of variable pitch, particle flattening, particle curvature, imaging noise and variable negative stain on two dimensional (2D) real-space reconstructions using electron density models of the sickle cell hemoglobin (HbS) macrofiber. The HbS macrofiber, a 500 A diameter helical particle with a pitch of about 10,000 A, is formed in vitro at pH < 7.1. The Fourier transform of the particle is extremely complex due to disorder, large particle size, and variable pitch, making the indexing required for Fourier-Bessel reconstructions very difficult. However, real-space techniques require fewer assumptions about the particle order. Preliminary particle reconstructions have led us to consider the effect of non-ideal particle imaging on the reconstruction result." @default.
- W3035774801 created "2020-06-25" @default.
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- W3035774801 date "1985-08-01" @default.
- W3035774801 modified "2023-09-27" @default.
- W3035774801 title "Real-Space Reconstructions of Non-Ideal Helical Models" @default.
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- W3035774801 doi "https://doi.org/10.1017/s0424820100118412" @default.
- W3035774801 hasPublicationYear "1985" @default.
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