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• W3035909306 abstract "The concept of small-molecule mimicry even of weak microbial metabolites present in rodents and humans, as a means to expand drug repertoires, is new. Hitherto, there are few proof-of-concept papers demonstrating utility of this concept. More recently, papers demonstrating mimicry of intestinal microbial metabolites could expand the drug repertoire for diseases such as inflammatory bowel disease (IBD). We opine that, as more functional metabolite–receptor pairings are discovered, small-molecule metabolite mimicry could be a significant effort in drug discovery." @default.
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• W3035909306 date "2020-09-01" @default.
• W3035909306 modified "2023-10-17" @default.
• W3035909306 title "Human microbial metabolite mimicry as a strategy to expand the chemical space of potential drugs" @default.
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• W3035909306 doi "https://doi.org/10.1016/j.drudis.2020.06.007" @default.
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