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• W3036059004 abstract "A system has been developed to allow highly specific derivatization of the thymine bases of DNA with mercurial compounds wich should be visible in the high resolution scanning electron microscope. Three problems must be completely solved before this staining system will be useful for base sequencing by electron microscopy: 1) the staining must be shown to be highly specific for one base, 2) the stained DNA must remain intact in a high vacuum on a thin support film suitable for microscopy, 3) the arrangement of heavy atoms on the DNA must be determined by the elastic scattering of electrons in the microscope without loss or large movement of heavy atoms." @default.
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• W3036059004 date "1972-08-01" @default.
• W3036059004 modified "2023-09-25" @default.
• W3036059004 title "A Base Specific Single Heavy Atom Stain for Electron Microscopy" @default.
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• W3036059004 doi "https://doi.org/10.1017/s0424820100094176" @default.
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