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- W3036331343 abstract "Progestagen minipills containing .5 mg chlormadinone acetate .3 mg norethisterone .05 mg norgestrel .03 mg d-norgestrel or .5 mg lynestrenol are discussed with respect to side effects laboratory tests menstrual cycle aberrations and contraceptive security. Pill side effects are absent few or less frequent than before in particular migraine headaches dysmenorrhea and premenstrual syndrome. Breast pain has been reported though and elevated urinary estrogens seen after prolonged use of chlormadinone acetate and norethisterone may cause them. Minipills are indicated for women who cannot tolerate conventional pills. All laboratory tests remain normal except that elevated triglycerides have been reported with norethisterone. The most important drawbacks are spotting metrorrhagia and long cycles or amenorrhea leading to discontinuation by 15-20% of minipill users. There are wide variations among geographic and racial groups. Contraceptive efficacy also ranges widely with Pearl indices of 0-15%; failure is possible if even 1 pill is forgotten or taken at a different time. The type of pill formulation i.e. tablet or capsule and the half-life of the particular progestagen influence contraceptive efficacy." @default.
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- W3036331343 date "1975-09-01" @default.
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- W3036331343 title "[Advantages and drawbacks of the mini-pill]." @default.
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