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- W3036532479 abstract "We have developed a new Fourier transform infrared chemical imaging technique which, when coupled with powerful multivariate data processing techniques, allows the visualization of complex intrinsic chemical distributions in biological materials with the potential for performing rapid histological examinations. Integrating spectroscopy with sample visualization and digital image processing is a potent combination of what have traditionally been two distinct methods for studying the chemistry and morphology of a sample. This synergy has been referred to as chemical imaging or hyperspectral imaging and has wide ranging applications in material characterization. In the infrared spectral region the technique relies on the use of infrared focal-plane array detectors, a newly developed commercial technology. These arrays are used in conjunction with standard Cassegrainian infrared microscopes and commercially available step-scan Michelson FTIR spectrometers to construct infrared imaging systems capable of collecting tens of thousands of spatially resolved infrared spectra (3μm 2 ) with less than 1 minute of data acquisition time. The data sets contain both spatial and spectral information and typically consist of hundreds of images resolved in frequency space (wavenumbers, cm −1 ), with each image containing many tens of thousands of pixels." @default.
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- W3036532479 date "1996-08-11" @default.
- W3036532479 modified "2023-09-27" @default.
- W3036532479 title "Fourier transform infrared chemical imaging microscopy: Applications in neurotoxicity and pathology" @default.
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- W3036532479 doi "https://doi.org/10.1017/s0424820100163757" @default.
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