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• W3036638683 abstract "Epithelial–mesenchymal transitions (EMTs) generate hybrid phenotypes with an enhanced ability to adapt to diverse microenvironments encountered during the metastatic spread. Accordingly, EMTs play a crucial role in the biology of circulating tumor cells (CTCs) and contribute to their heterogeneity. Here, we review major EMT-driven properties that may help hybrid Epithelial/Mesenchymal CTCs to survive in the bloodstream and accomplish early phases of metastatic colonization. We then discuss how interrogating EMT in CTCs as a companion biomarker could help refine cancer patient management, further supporting the relevance of CTCs in personalized medicine." @default.
• W3036638683 created "2020-06-25" @default.
• W3036638683 creator A5003553707 @default.
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• W3036638683 creator A5051405381 @default.
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• W3036638683 date "2020-06-19" @default.
• W3036638683 modified "2023-09-26" @default.
• W3036638683 title "EMT-Associated Heterogeneity in Circulating Tumor Cells: Sticky Friends on the Road to Metastasis" @default.
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