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- W3036680648 abstract "Abstract Human exposure to mixtures of perfluoroalkyl and polyfluoroalkyl substances (PFASs) constitutes an important issue in environmental epidemiology and the adoption of more holistic approaches to reduce the uncertainties associated with their human health effects is a critical research need. The ‘exposome’, defined as the totality of environmental (i.e. nongenetic) exposures from conception onward represents a new path towards understanding environmental determinants of human disease by assessing the multitude of exposures and risk of adverse health outcomes that occur over a lifetime. Here, we review the limitations of traditional approaches to PFAS health assessments and explore how the exposome approach may be able to address such issues. We discuss the advantages and disadvantages of exposomic research and its implementation into human health studies, and provide suggestions for future research to adopt the exposome approach to better characterise the overall influence of PFAS exposures on human health." @default.
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- W3036680648 date "2020-06-01" @default.
- W3036680648 modified "2023-09-24" @default.
- W3036680648 title "Characterising the effects of per- and polyfluoroalkyl substances (PFASs) on health and disease: An opportunity for exposomics?" @default.
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- W3036680648 doi "https://doi.org/10.1016/j.coesh.2020.05.006" @default.
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