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- W303669758 abstract "This chapter discusses the carrier-mediated uptake of sugars through the basolateral membrane of colon epithelium. The main site for intestinal absorption of sugars and amino acids is the small intestine. Both sugars and amino acids are absorbed from the small intestine by active transport processes. The sugar transport system in the basolateral membrane of colon epithelium behaves differently in this respect from the Na-dependent sugar transport mechanism in the small intestinal brush border membrane, which is more sensitive to phlorizin than to phloretin. In contrast to the colon epithelium, the sugar transport system of the basolateral membrane in the small intestinal epithelium is only affected by phloretin but not by phlorizin. There seems to be some difference between the basolateral sugar transport system of the small and large intestine. Intracellular uptake of 2-DG and 3-MG from the antiluminal side of colon epithelium is rather Na+-independent, while there is a clear-cut Na+ dependence in the uptake of the nonmetabolizable amino acid α-aminoisobutyric acid. The Na concentration of the incubation medium was reduced from 143 to 30 mmol/1 by replacing the NaCl of the Krebs–Henseleit buffer by choline chloride. Similar effects were obtained when NaCl was replaced by LiCl." @default.
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- W303669758 date "1981-01-01" @default.
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- W303669758 title "CARRIER-MEDIATED UPTAKE OF SUGARS THROUGH THE BASOLATERAL MEMBRANE OF COLON EPITHELIUM" @default.
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- W303669758 doi "https://doi.org/10.1016/b978-0-08-026825-5.50072-3" @default.
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