FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3036699323> ?p ?o ?g. }

• W3036699323 endingPage "309" @default.
• W3036699323 startingPage "309" @default.
• W3036699323 abstract "Background and objective: Changes in cannabis legalization regimes in several countries have influenced the diversification of cannabis use. There is an ever-increasing number of cannabis forms available, which are gaining popularity for both recreational and therapeutic use. From a therapeutic perspective, oral cannabis containing Δ-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) is a promising route of administration but there is still little information about its pharmacokinetics (PK) effects in humans. The purpose of this systematic review is to provide a general overview of the available PK data on cannabis and THC after oral administration. Materials and Methods: A search of the published literature was conducted using the PubMed database to collect available articles describing the PK data of THC after oral administration in humans. Results: The literature search yielded 363 results, 26 of which met our inclusion criteria. The PK of oral THC has been studied using capsules (including oil content), tablets, baked goods (brownies and cookies), and oil and tea (decoctions). Capsules and tablets, which mainly correspond to pharmaceutical forms, were found to be the oral formulations most commonly studied. Overall, the results reflect the high variability in the THC absorption of oral formulations, with delayed peak plasma concentrations compared to other routes of administration. Conclusions: Oral THC has a highly variable PK profile that differs between formulations, with seemingly higher variability in baked goods and oil forms. Overall, there is limited information available in this field. Therefore, further investigations are required to unravel the unpredictability of oral THC administration to increase the effectiveness and safety of oral formulations in medicinal use." @default.
• W3036699323 created "2020-06-25" @default.
• W3036699323 creator A5002872494 @default.
• W3036699323 creator A5003912123 @default.
• W3036699323 creator A5033539160 @default.
• W3036699323 creator A5034073666 @default.
• W3036699323 creator A5036831245 @default.
• W3036699323 creator A5058384218 @default.
• W3036699323 creator A5074614955 @default.
• W3036699323 creator A5076453098 @default.
• W3036699323 creator A5082502601 @default.
• W3036699323 creator A5083373223 @default.
• W3036699323 date "2020-06-23" @default.
• W3036699323 modified "2023-10-16" @default.
• W3036699323 title "Oral Administration of Cannabis and Δ-9-tetrahydrocannabinol (THC) Preparations: A Systematic Review" @default.
• W3036699323 cites W1608227749 @default.
• W3036699323 cites W1772744802 @default.
• W3036699323 cites W1851678352 @default.
• W3036699323 cites W1918174127 @default.
• W3036699323 cites W1945751328 @default.
• W3036699323 cites W2002858950 @default.
• W3036699323 cites W2003462812 @default.
• W3036699323 cites W2005501262 @default.
• W3036699323 cites W2022271647 @default.
• W3036699323 cites W2075543597 @default.
• W3036699323 cites W2091487276 @default.
• W3036699323 cites W2095587092 @default.
• W3036699323 cites W2095627608 @default.
• W3036699323 cites W2096273698 @default.
• W3036699323 cites W2102117682 @default.
• W3036699323 cites W2106954948 @default.
• W3036699323 cites W2110403636 @default.
• W3036699323 cites W2116460935 @default.
• W3036699323 cites W2149642074 @default.
• W3036699323 cites W2151173006 @default.
• W3036699323 cites W2169462011 @default.
• W3036699323 cites W2169616495 @default.
• W3036699323 cites W2282484587 @default.
• W3036699323 cites W2336815228 @default.
• W3036699323 cites W2529968311 @default.
• W3036699323 cites W2531420938 @default.
• W3036699323 cites W2544036350 @default.
• W3036699323 cites W2583134819 @default.
• W3036699323 cites W2586473686 @default.
• W3036699323 cites W2587433492 @default.
• W3036699323 cites W2588176132 @default.
• W3036699323 cites W2591427933 @default.
• W3036699323 cites W2607101187 @default.
• W3036699323 cites W2744955205 @default.
• W3036699323 cites W2751824458 @default.
• W3036699323 cites W2786924077 @default.
• W3036699323 cites W2790187113 @default.
• W3036699323 cites W2872043390 @default.
• W3036699323 cites W2886469289 @default.
• W3036699323 cites W2890337129 @default.
• W3036699323 cites W2897896107 @default.
• W3036699323 cites W2902043534 @default.
• W3036699323 cites W2902255424 @default.
• W3036699323 cites W2935279248 @default.
• W3036699323 cites W2943418795 @default.
• W3036699323 cites W2945772836 @default.
• W3036699323 cites W2984940500 @default.
• W3036699323 cites W2991113249 @default.
• W3036699323 cites W2997769382 @default.
• W3036699323 cites W3001650767 @default.
• W3036699323 cites W3003606793 @default.
• W3036699323 cites W3008269868 @default.
• W3036699323 cites W3012161732 @default.
• W3036699323 cites W3025972513 @default.
• W3036699323 doi "https://doi.org/10.3390/medicina56060309" @default.
• W3036699323 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7353904" @default.
• W3036699323 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32585912" @default.
• W3036699323 hasPublicationYear "2020" @default.
• W3036699323 type Work @default.
• W3036699323 sameAs 3036699323 @default.
• W3036699323 citedByCount "33" @default.
• W3036699323 countsByYear W30366993232020 @default.
• W3036699323 countsByYear W30366993232021 @default.
• W3036699323 countsByYear W30366993232022 @default.
• W3036699323 countsByYear W30366993232023 @default.
• W3036699323 crossrefType "journal-article" @default.
• W3036699323 hasAuthorship W3036699323A5002872494 @default.
• W3036699323 hasAuthorship W3036699323A5003912123 @default.
• W3036699323 hasAuthorship W3036699323A5033539160 @default.
• W3036699323 hasAuthorship W3036699323A5034073666 @default.
• W3036699323 hasAuthorship W3036699323A5036831245 @default.
• W3036699323 hasAuthorship W3036699323A5058384218 @default.
• W3036699323 hasAuthorship W3036699323A5074614955 @default.
• W3036699323 hasAuthorship W3036699323A5076453098 @default.
• W3036699323 hasAuthorship W3036699323A5082502601 @default.
• W3036699323 hasAuthorship W3036699323A5083373223 @default.
• W3036699323 hasBestOaLocation W30366993231 @default.
• W3036699323 hasConcept C118552586 @default.
• W3036699323 hasConcept C126322002 @default.
• W3036699323 hasConcept C170493617 @default.
• W3036699323 hasConcept C181389837 @default.
• W3036699323 hasConcept C2776895053 @default.
• W3036699323 hasConcept C2777056318 @default.

• next