FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3036745897> ?p ?o ?g. }

• W3036745897 abstract "The aim of this study was to investigate the possible protective role of Hydrogen sulfide on chronic unpredictable stress (CUS) -induced gastric lesions. Materials and methods: 40 rats were divided into 4 groups: control group, stressed rats group, stressed + Aminooxyacetic acid (AOAA) (inhibitor of H2S synthesis; 50mg/kg/48hour; IP), stressed + Sodium hydrosulfide (NaHS) (donor of H2S, 5mg/kg/48hour; IP). In all the groups exposed to CUS, a set of chronic unpredictable stressors was applied for 6 weeks in random order. At the end of experimental protocol blood samples, gastric content and gastric tissues samples were collected. Gastric tissues histopathological changes were evaluated by macroscopic and microscopic examination. Gastric content pH, serum MDA level, whole blood GSH level were estimated. Expression of Caspase-3 (apoptotic marker) and BCL-xl (anti-apoptotic marker) was assessed by immunohistochemistry. Results: In all the groups exposed to CUS, there was a significant reduction in gastric pH value and a range of gastric lesions ranging from superficial to deep ulceration as evident by macroscopic and microscopic examination. Also, there was significant elevation in MDA serum level and significant reduction in anti-oxidant GSH blood level. In all stressed rats, the expression of Caspase-3 was significantly higher whereas a significant decrease in expression of anti-apoptotic protein BCL-xl was observed. These findings were aggravated by AOAA while using NaHS improved them. Conclusion: it seems that increasing bioavailability of H2S could have a protective role against CUS induced gastric lesions. The results suggest that this protection could be through anti-oxidant and anti-apoptotic effects." @default.
• W3036745897 created "2020-06-25" @default.
• W3036745897 creator A5019265319 @default.
• W3036745897 creator A5024925972 @default.
• W3036745897 creator A5031872264 @default.
• W3036745897 creator A5076855375 @default.
• W3036745897 creator A5091530849 @default.
• W3036745897 date "2020-06-01" @default.
• W3036745897 modified "2023-10-18" @default.
• W3036745897 title "The Role of Hydrogen Sulfide in Chronic Unpredictable Stress-Induced Gastric Lesions." @default.
• W3036745897 cites W1580678534 @default.
• W3036745897 cites W1598450487 @default.
• W3036745897 cites W1636270625 @default.
• W3036745897 cites W1942962978 @default.
• W3036745897 cites W1967429436 @default.
• W3036745897 cites W1979757145 @default.
• W3036745897 cites W1982594459 @default.
• W3036745897 cites W1992662939 @default.
• W3036745897 cites W2007936423 @default.
• W3036745897 cites W2016101932 @default.
• W3036745897 cites W2059401269 @default.
• W3036745897 cites W2061050258 @default.
• W3036745897 cites W2074411064 @default.
• W3036745897 cites W2076786048 @default.
• W3036745897 cites W2081225560 @default.
• W3036745897 cites W2096984233 @default.
• W3036745897 cites W2116612251 @default.
• W3036745897 cites W2133511841 @default.
• W3036745897 cites W2134252021 @default.
• W3036745897 cites W2146749273 @default.
• W3036745897 cites W2152247516 @default.
• W3036745897 cites W2162082164 @default.
• W3036745897 cites W2169746496 @default.
• W3036745897 cites W2261667678 @default.
• W3036745897 cites W2266929960 @default.
• W3036745897 cites W2413123575 @default.
• W3036745897 cites W2588140199 @default.
• W3036745897 cites W2598376927 @default.
• W3036745897 cites W2938789226 @default.
• W3036745897 cites W2086643536 @default.
• W3036745897 doi "https://doi.org/10.21608/besps.2019.16189.1032" @default.
• W3036745897 hasPublicationYear "2020" @default.
• W3036745897 type Work @default.
• W3036745897 sameAs 3036745897 @default.
• W3036745897 citedByCount "0" @default.
• W3036745897 crossrefType "journal-article" @default.
• W3036745897 hasAuthorship W3036745897A5019265319 @default.
• W3036745897 hasAuthorship W3036745897A5024925972 @default.
• W3036745897 hasAuthorship W3036745897A5031872264 @default.
• W3036745897 hasAuthorship W3036745897A5076855375 @default.
• W3036745897 hasAuthorship W3036745897A5091530849 @default.
• W3036745897 hasBestOaLocation W30367458971 @default.
• W3036745897 hasConcept C126322002 @default.
• W3036745897 hasConcept C142724271 @default.
• W3036745897 hasConcept C178790620 @default.
• W3036745897 hasConcept C185592680 @default.
• W3036745897 hasConcept C190283241 @default.
• W3036745897 hasConcept C204232928 @default.
• W3036745897 hasConcept C2776151105 @default.
• W3036745897 hasConcept C2777397205 @default.
• W3036745897 hasConcept C2780519940 @default.
• W3036745897 hasConcept C2780564542 @default.
• W3036745897 hasConcept C518881349 @default.
• W3036745897 hasConcept C55493867 @default.
• W3036745897 hasConcept C71924100 @default.
• W3036745897 hasConcept C90924648 @default.
• W3036745897 hasConceptScore W3036745897C126322002 @default.
• W3036745897 hasConceptScore W3036745897C142724271 @default.
• W3036745897 hasConceptScore W3036745897C178790620 @default.
• W3036745897 hasConceptScore W3036745897C185592680 @default.
• W3036745897 hasConceptScore W3036745897C190283241 @default.
• W3036745897 hasConceptScore W3036745897C204232928 @default.
• W3036745897 hasConceptScore W3036745897C2776151105 @default.
• W3036745897 hasConceptScore W3036745897C2777397205 @default.
• W3036745897 hasConceptScore W3036745897C2780519940 @default.
• W3036745897 hasConceptScore W3036745897C2780564542 @default.
• W3036745897 hasConceptScore W3036745897C518881349 @default.
• W3036745897 hasConceptScore W3036745897C55493867 @default.
• W3036745897 hasConceptScore W3036745897C71924100 @default.
• W3036745897 hasConceptScore W3036745897C90924648 @default.
• W3036745897 hasLocation W30367458971 @default.
• W3036745897 hasOpenAccess W3036745897 @default.
• W3036745897 hasPrimaryLocation W30367458971 @default.
• W3036745897 hasRelatedWork W13024533 @default.
• W3036745897 hasRelatedWork W13327493 @default.
• W3036745897 hasRelatedWork W3044111 @default.
• W3036745897 hasRelatedWork W3216860 @default.
• W3036745897 hasRelatedWork W4231221 @default.
• W3036745897 hasRelatedWork W4620714 @default.
• W3036745897 hasRelatedWork W5443970 @default.
• W3036745897 hasRelatedWork W6480816 @default.
• W3036745897 hasRelatedWork W716708 @default.
• W3036745897 hasRelatedWork W8327052 @default.
• W3036745897 isParatext "false" @default.
• W3036745897 isRetracted "false" @default.
• W3036745897 magId "3036745897" @default.
• W3036745897 workType "article" @default.