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- W3036746722 abstract "Compound 48/80, a mast cell degranulating agent, produces marked hypotension in the rat. Thirty minutes after intravenous treatment with compound 48/80 there is a significant increase in blood-glucose with a concommitant decrease in hepatic glycogen similar to that observed in shock-like states. Electron microscopic observations of hepatocytes from rats treated with 48/80 have shown an apparent decrease in hepatic glycogen and increase in smooth endoplasmic reticulum (SER). Mitochondria in these cells seemed to contain fewer matrix granules. The present analysis was performed to quantify these observations. Since light microscopic observations of tissue from these rats revealed an apparent greater depletion of glycogen in the portal areas (unpublished observation), hepatic portal cells were analyzed in this initial study." @default.
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- W3036746722 date "1982-08-13" @default.
- W3036746722 modified "2023-09-26" @default.
- W3036746722 title "Morphometric Analysis of Portal Hepatocytes from Rats Treated with Compound 48/80" @default.
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- W3036746722 doi "https://doi.org/10.1017/s0424820100053127" @default.
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