Matches in SemOpenAlex for { <https://semopenalex.org/work/W3036766025> ?p ?o ?g. }
- W3036766025 abstract "Abstract The large‐conductance calcium‐activated potassium channel (BK Ca ) plays an important role in the regulation of insect neural circuits and locomotion, and thus is a potential target of insecticides. In this study, iberiotoxin, an inhibitor of BK Ca , was found to prolong the anesthetic time of ethyl acetate on Plutella xylostella larvae. Therefore, the coding sequence of slowpoke gene coding the alpha subunit of BK Ca was cloned to investigate the function of this channel in P. xylostella , and the gene expression profile in the developmental stages and tissues was also characterized. The total length of pxslo DNA was more than 19.9 kb, which harbored four alternative splicing sites (ASP‐A, ASP‐C, ASP‐E, and ASP‐G), and the coding sequence of pxslo with the highest frequency of splicing (GenBank ID: MN938456) was 3,405 base pair. The characterized PxSlo protein contained conserved domains previously identified in other insects. Quantitative reverse transcription‐polymerase chain reaction analysis showed that pxslo was expressed in all the developmental stages of P. xylostella , with the highest level in adults. In the larval stage, pxslo was mainly expressed in the head and epidermis, while a limited protein was expressed in the midgut. In the adult stage, pxslo was highly expressed in the head, followed by in the ovarian tubule, and was not expressed in the testis or wings. These results suggest that BK Ca plays an important physiological role in P. xylostella and provides useful information for the functional study and screening of BK Ca inhibitors." @default.
- W3036766025 created "2020-06-25" @default.
- W3036766025 creator A5013120629 @default.
- W3036766025 creator A5032218251 @default.
- W3036766025 creator A5034899868 @default.
- W3036766025 creator A5047517748 @default.
- W3036766025 creator A5050573380 @default.
- W3036766025 creator A5057117256 @default.
- W3036766025 creator A5061311697 @default.
- W3036766025 creator A5067510740 @default.
- W3036766025 creator A5077108182 @default.
- W3036766025 date "2020-06-17" @default.
- W3036766025 modified "2023-10-18" @default.
- W3036766025 title "Expression and alternative splicing analysis of a large‐conductance calcium‐activated potassium channel gene inPlutella xylostella" @default.
- W3036766025 cites W1598300390 @default.
- W3036766025 cites W1931784730 @default.
- W3036766025 cites W1970175010 @default.
- W3036766025 cites W1971038847 @default.
- W3036766025 cites W1971414885 @default.
- W3036766025 cites W1980121369 @default.
- W3036766025 cites W1996051526 @default.
- W3036766025 cites W1998428146 @default.
- W3036766025 cites W1998719957 @default.
- W3036766025 cites W2002500727 @default.
- W3036766025 cites W2007860569 @default.
- W3036766025 cites W2014158880 @default.
- W3036766025 cites W2022642022 @default.
- W3036766025 cites W2024022389 @default.
- W3036766025 cites W2031571254 @default.
- W3036766025 cites W2048452598 @default.
- W3036766025 cites W2063845237 @default.
- W3036766025 cites W2064608326 @default.
- W3036766025 cites W2071969879 @default.
- W3036766025 cites W2079687455 @default.
- W3036766025 cites W2085534162 @default.
- W3036766025 cites W2092770613 @default.
- W3036766025 cites W2096277719 @default.
- W3036766025 cites W2100081225 @default.
- W3036766025 cites W2120961946 @default.
- W3036766025 cites W2126219184 @default.
- W3036766025 cites W2126992918 @default.
- W3036766025 cites W2132742467 @default.
- W3036766025 cites W2135077777 @default.
- W3036766025 cites W2135178190 @default.
- W3036766025 cites W2144819568 @default.
- W3036766025 cites W2152709239 @default.
- W3036766025 cites W2162231449 @default.
- W3036766025 cites W2169117352 @default.
- W3036766025 cites W2610112373 @default.
- W3036766025 cites W2610826702 @default.
- W3036766025 cites W2796209794 @default.
- W3036766025 cites W2802038365 @default.
- W3036766025 cites W2950544572 @default.
- W3036766025 cites W2965850689 @default.
- W3036766025 cites W2969247343 @default.
- W3036766025 cites W2971232193 @default.
- W3036766025 cites W2975738179 @default.
- W3036766025 doi "https://doi.org/10.1002/arch.21720" @default.
- W3036766025 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32557681" @default.
- W3036766025 hasPublicationYear "2020" @default.
- W3036766025 type Work @default.
- W3036766025 sameAs 3036766025 @default.
- W3036766025 citedByCount "0" @default.
- W3036766025 crossrefType "journal-article" @default.
- W3036766025 hasAuthorship W3036766025A5013120629 @default.
- W3036766025 hasAuthorship W3036766025A5032218251 @default.
- W3036766025 hasAuthorship W3036766025A5034899868 @default.
- W3036766025 hasAuthorship W3036766025A5047517748 @default.
- W3036766025 hasAuthorship W3036766025A5050573380 @default.
- W3036766025 hasAuthorship W3036766025A5057117256 @default.
- W3036766025 hasAuthorship W3036766025A5061311697 @default.
- W3036766025 hasAuthorship W3036766025A5067510740 @default.
- W3036766025 hasAuthorship W3036766025A5077108182 @default.
- W3036766025 hasConcept C104317684 @default.
- W3036766025 hasConcept C134018914 @default.
- W3036766025 hasConcept C153911025 @default.
- W3036766025 hasConcept C194583182 @default.
- W3036766025 hasConcept C36823959 @default.
- W3036766025 hasConcept C54355233 @default.
- W3036766025 hasConcept C61144316 @default.
- W3036766025 hasConcept C83743174 @default.
- W3036766025 hasConcept C86803240 @default.
- W3036766025 hasConcept C95444343 @default.
- W3036766025 hasConceptScore W3036766025C104317684 @default.
- W3036766025 hasConceptScore W3036766025C134018914 @default.
- W3036766025 hasConceptScore W3036766025C153911025 @default.
- W3036766025 hasConceptScore W3036766025C194583182 @default.
- W3036766025 hasConceptScore W3036766025C36823959 @default.
- W3036766025 hasConceptScore W3036766025C54355233 @default.
- W3036766025 hasConceptScore W3036766025C61144316 @default.
- W3036766025 hasConceptScore W3036766025C83743174 @default.
- W3036766025 hasConceptScore W3036766025C86803240 @default.
- W3036766025 hasConceptScore W3036766025C95444343 @default.
- W3036766025 hasFunder F4320321001 @default.
- W3036766025 hasIssue "1" @default.
- W3036766025 hasLocation W30367660251 @default.
- W3036766025 hasLocation W30367660252 @default.
- W3036766025 hasOpenAccess W3036766025 @default.
- W3036766025 hasPrimaryLocation W30367660251 @default.
- W3036766025 hasRelatedWork W1573549078 @default.