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- W3036875791 abstract "Photography-based teledermatology has the potential to increase patient access to clinical trials, in part by removing geographic barriers that limit participation to those who reside near a trial site. Here we present interim results from a study evaluating digital photography as a method of assessing rosacea severity, in comparison with in-person methods. Eight dermatology raters performed in-person assessments of rosacea patients at a clinic in Los Angeles, California. Rosacea severity was graded using the Clinician’s Erythema Assessment (CEA), Investigator’s Global Assessment (IGA), and inflammatory lesion count. During the same visit, study participants were trained to take six self-photographs of their face using an iPhone SE. These photographs were housed in our cloud-based clinical trial software platform. Following a period of 28 days, raters performed rosacea severity assessments on the same patients they assessed in clinic, utilizing the digital photographs described above. To date, 34 patients (of a planned sample size of 70) have completed the study activities as outlined. Using the intraclass correlation coefficient (ICC), we compared agreement between photographic assessments of rosacea severity with the same assessments performed in-person. The ICC for CEA was 0.75 (95% CI 0.66-0.84), for IGA 0.83 (95% CI 0.74-0.89), and for total inflammatory lesion count 0.91 (95% CI 0.84-0.95), indicating agreement ranging from good to excellent. Interim results from this study indicate that patient self-photographs taken on an iPhone can be used to reliably assess rosacea severity, supporting the integration of photography-based teledermatology into future clinical trials for rosacea." @default.
- W3036875791 created "2020-06-25" @default.
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- W3036875791 date "2020-07-01" @default.
- W3036875791 modified "2023-09-27" @default.
- W3036875791 title "491 Interim results from a comparative method validation study evaluating the use of digital photographs versus in-person assessment of rosacea" @default.
- W3036875791 doi "https://doi.org/10.1016/j.jid.2020.03.500" @default.
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