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• W3036954949 abstract "Invasive fungal diseases are a leading cause of mortality among immunocompromised populations. Treatment is notoriously difficult due to the limited number of antifungal drugs as well as the emergence of drug resistance. Tamoxifen (TAM), a selective estrogen receptor modulator frequently used for the treatment of breast cancer, has been found to have antifungal activities and may be a useful addition to the agents used to treat fungal infectious diseases. However, the molecular mechanisms underlying its antifungal actions remain obscure." @default.
• W3036954949 created "2020-06-25" @default.
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• W3036954949 date "2020-08-20" @default.
• W3036954949 modified "2023-09-27" @default.
• W3036954949 title "NADPH-Cytochrome P450 Reductase Ccr1 Is a Target of Tamoxifen and Participates in Its Antifungal Activity via Regulating Cell Wall Integrity in Fission Yeast" @default.
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• W3036954949 doi "https://doi.org/10.1128/aac.00079-20" @default.
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