FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3037047110> ?p ?o ?g. }

• W3037047110 endingPage "363" @default.
• W3037047110 startingPage "357" @default.
• W3037047110 abstract "In this study, we aimed to compare the antimicrobial effects of bupivacaine and fentanyl citrate and to reveal the impact on antimicrobial effect potential in the case of combined use. In vitro prospective study. University Clinical Microbiology Laboratory. In our study, in vitro antimicrobial effect of 0.05 mg.mL-1 fentanyl citrate, 5 mg.mL-1 bupivacaine were tested against Staphylococcus aureus American Type Culture Collection (ATCC) 29213, Pseudomonas aeruginosa ATCC 27853, Klebsiella pneumoniae ATCC 13883, Escherichia coli ATCC 25922 and Candida albicans ATCC 10231 as Group F (Fentanyl Citrate) and Group B (Bupivacaine), respectively. S. aureus ATCC 29213, P. aeruginosa ATCC 27853, Klebsiella pneumoniae ATCC 13883 and Escherichia coli ATCC 25922 were cultured onto Mueller Hinton agar (Oxoid, UK) plates and Candida albicans ATCC 10231 were cultured onto Sabouraud dextrose agar (Oxoid, UK) plates for 18−24 hours at 37 °C. In terms of inhibition zone diameters, S. Aureus ATCC 29213, P. aeruginosa ATCC 27853, and C. albicans ATCC10231 values obtained after 12 and 24 hours of incubation ​​were significantly higher in Group F than Group B (p < 0.001). In terms of inhibition zone diameters, E. coli ATCC 25922, and K. pneumomiae ATCC 13883 values obtained after 12 and 24 hours of incubation ​​were significantly higher in Group B than Group F (p < 0.001, E. coli 12ª hour p = 0.005). Addition of fentanyl to Local Anesthetics (LAs) is often preferred in regional anesthesia applications in today's practice owing especially to its effect on decreasing the local anesthetic dose and increasing analgesia quality and patient satisfaction. However, when the fact that fentanyl antagonized the antimicrobial effects of LAs in the studies is taken into account, it might be though that it contributes to an increase in infection complications. When the fact that fentanyl citrate which was used in our study and included hydrochloric acid and sodium hydroxide as protective agents, broadened the antimicrobial effect spectrum of LAs, had no antagonistic effect and showed a synergistic antimicrobial effect against E. Coli is considered, we are of the opinion that the addition of fentanyl to LAs would contribute significantly in preventing the increasing regional anesthesia infection complications. O objetivo do presente estudo foi comparar os efeitos antimicrobianos da bupivacaína e citrato de fentanil e revelar o impacto no potencial do efeito antimicrobiano no caso de uso combinado. Estudo prospectivo in vitro. Laboratório de Microbiologia Clínica da Universidade. Em nosso estudo, os efeitos antimicrobianos in vitro do citrato de fentanil na concentração de 0,05 mg.mL-1 – Grupo F e da bupivacaína na concentração de 5 mg.mL-1 – Grupo B foram testados em culturas de Staphylococcus aureus ATCC 29213 (do inglês American Type Culture Collection 29213), Pseudomonas aeruginosa ATCC 27853, Klebsiella pneumoniae ATCC 13883, Escherichia coli ATCC 25922 e Candida albicans ATCC 10231. As culturas de S. aureus ATCC 29213, P. aeruginosa ATCC 27853, Klebsiella pneumoniae ATCC 13883 e Escherichia coli ATCC 25922 foram semeadas em placas de ágar Mueller Hinton (Oxoid, Reino Unido), e a cultura de Candida albicans ATCC 10231 foi realizada em placa de ágar Sabouraud dextrose (Oxoid, Reino Unido) durante 18−24 horas a 37 °C. Com relação ao diâmetro da zona de inibição, os valores de S. aureus ATCC 29213, P. aeruginosa ATCC 27853 e C. albicans ATCC10231 obtidos após 12 e 24 horas de incubação foram significantemente maiores no Grupo F do que no Grupo B (p < 0,001). Os valores do diâmetro da zona de inibição das culturas de E. coli ATCC 25922 e K. pneumomiae ATCC 13883 obtidos após 12 e 24 horas de incubação foram significantemente maiores no Grupo B do que no Grupo F (p < 0,001, E. coli na 12ª hora p = 0,005) A preferência atual e frequente pela adição de fentanil aos Anestésicos Locais (AL) para a realização de anestesia regional se deve sobretudo à possibilidade de redução da dose do anestésico local, a melhora na qualidade da analgesia e a satisfação do paciente. No entanto, ao considerar estudos em que o fentanil antagonizou o efeito antimicrobiano dos AL, pode-se pensar que esse fato contribua para aumento de complicação infecciosa. O citrato de fentanil usado em nosso estudo, contendo ácido clorídrico e hidróxido de sódio como agentes conservantes, ampliou o espectro de efeitos antimicrobianos dos AL, não teve efeito antagônico e demonstrou efeito antimicrobiano sinérgico contra a E. coli. Acreditamos que a adição de fentanil aos anestésicos locais traria importante contribuição na prevenção das crescentes complicações por infecção da anestesia regional." @default.
• W3037047110 created "2020-07-02" @default.
• W3037047110 creator A5013917448 @default.
• W3037047110 creator A5048032592 @default.
• W3037047110 creator A5071754999 @default.
• W3037047110 date "2020-07-01" @default.
• W3037047110 modified "2023-09-27" @default.
• W3037047110 title "Antimicrobial effects of fentanyl and bupivacaine: an in vitro study" @default.
• W3037047110 cites W134518677 @default.
• W3037047110 cites W1834591633 @default.
• W3037047110 cites W1979944856 @default.
• W3037047110 cites W2021180004 @default.
• W3037047110 cites W2046621095 @default.
• W3037047110 cites W2049685361 @default.
• W3037047110 cites W2069335874 @default.
• W3037047110 cites W2081588657 @default.
• W3037047110 cites W2092465520 @default.
• W3037047110 cites W2101574868 @default.
• W3037047110 cites W2113001906 @default.
• W3037047110 cites W2315704745 @default.
• W3037047110 cites W2410932419 @default.
• W3037047110 cites W2562374158 @default.
• W3037047110 cites W2735084711 @default.
• W3037047110 cites W2904758541 @default.
• W3037047110 cites W2912615668 @default.
• W3037047110 cites W2947581522 @default.
• W3037047110 cites W2967469519 @default.
• W3037047110 cites W32197901 @default.
• W3037047110 doi "https://doi.org/10.1016/j.bjane.2020.04.026" @default.
• W3037047110 hasPublicationYear "2020" @default.
• W3037047110 type Work @default.
• W3037047110 sameAs 3037047110 @default.
• W3037047110 citedByCount "1" @default.
• W3037047110 countsByYear W30370471102023 @default.
• W3037047110 crossrefType "journal-article" @default.
• W3037047110 hasAuthorship W3037047110A5013917448 @default.
• W3037047110 hasAuthorship W3037047110A5048032592 @default.
• W3037047110 hasAuthorship W3037047110A5071754999 @default.
• W3037047110 hasBestOaLocation W30370471101 @default.
• W3037047110 hasConcept C104317684 @default.
• W3037047110 hasConcept C145081991 @default.
• W3037047110 hasConcept C185592680 @default.
• W3037047110 hasConcept C25642318 @default.
• W3037047110 hasConcept C2777058267 @default.
• W3037047110 hasConcept C2777637488 @default.
• W3037047110 hasConcept C2778660310 @default.
• W3037047110 hasConcept C2779489039 @default.
• W3037047110 hasConcept C2780917455 @default.
• W3037047110 hasConcept C4937899 @default.
• W3037047110 hasConcept C523546767 @default.
• W3037047110 hasConcept C54355233 @default.
• W3037047110 hasConcept C547475151 @default.
• W3037047110 hasConcept C55493867 @default.
• W3037047110 hasConcept C62643968 @default.
• W3037047110 hasConcept C86803240 @default.
• W3037047110 hasConcept C89423630 @default.
• W3037047110 hasConceptScore W3037047110C104317684 @default.
• W3037047110 hasConceptScore W3037047110C145081991 @default.
• W3037047110 hasConceptScore W3037047110C185592680 @default.
• W3037047110 hasConceptScore W3037047110C25642318 @default.
• W3037047110 hasConceptScore W3037047110C2777058267 @default.
• W3037047110 hasConceptScore W3037047110C2777637488 @default.
• W3037047110 hasConceptScore W3037047110C2778660310 @default.
• W3037047110 hasConceptScore W3037047110C2779489039 @default.
• W3037047110 hasConceptScore W3037047110C2780917455 @default.
• W3037047110 hasConceptScore W3037047110C4937899 @default.
• W3037047110 hasConceptScore W3037047110C523546767 @default.
• W3037047110 hasConceptScore W3037047110C54355233 @default.
• W3037047110 hasConceptScore W3037047110C547475151 @default.
• W3037047110 hasConceptScore W3037047110C55493867 @default.
• W3037047110 hasConceptScore W3037047110C62643968 @default.
• W3037047110 hasConceptScore W3037047110C86803240 @default.
• W3037047110 hasConceptScore W3037047110C89423630 @default.
• W3037047110 hasIssue "4" @default.
• W3037047110 hasLocation W30370471101 @default.
• W3037047110 hasLocation W30370471102 @default.
• W3037047110 hasLocation W30370471103 @default.
• W3037047110 hasLocation W30370471104 @default.
• W3037047110 hasLocation W30370471105 @default.
• W3037047110 hasOpenAccess W3037047110 @default.
• W3037047110 hasPrimaryLocation W30370471101 @default.
• W3037047110 hasRelatedWork W1801898498 @default.
• W3037047110 hasRelatedWork W1967858509 @default.
• W3037047110 hasRelatedWork W2048267026 @default.
• W3037047110 hasRelatedWork W2140839919 @default.
• W3037047110 hasRelatedWork W2170643866 @default.
• W3037047110 hasRelatedWork W2935726606 @default.
• W3037047110 hasRelatedWork W2944652277 @default.
• W3037047110 hasRelatedWork W3133673709 @default.
• W3037047110 hasRelatedWork W4226059590 @default.
• W3037047110 hasRelatedWork W7163209 @default.
• W3037047110 hasVolume "70" @default.
• W3037047110 isParatext "false" @default.
• W3037047110 isRetracted "false" @default.
• W3037047110 magId "3037047110" @default.
• W3037047110 workType "article" @default.