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- W3037065400 abstract "TYPE: Abstract Publication TOPIC: Pulmonary Manifestations of Systemic Disease PURPOSE: ILD is the most common involvement in CTD. The incidence of ILD in seronegative RA is very less common unless the longer duration of disease.The association between AIH and development of ILD has not been well characterized. Here we are presenting a case of IIP(NSIP) in Autoimmune hepatitis. METHODS: Liver Biopsy RESULTS: A 46 year old female was a k/c/o seronegative rheumatoid arthritis for 3 yrs not on regular treatment for 21/2 yrs.K/c/o Hypothyroid for 5yrs on regular treatment.Known diabetic for 5yrs on insulin.She came with c/o generalized fatigue,abdominal pain,nausea,vomiting, loa & low.Cect abdomen shows enlarged fatty liver with focal fatty sparing with altered parenchymal densities.Immunological profile showed all were Negative.Except ANA strongly positive.Liver biopsy had been done which showed Interface hepatitis.she was diagnosed as Autoimmune hepatitis.she was started on steroids.one month later she came with c/o breathlessness.CtChest showed patchy GGO’s,minimal subpleural,parenchymal fibrotic changes with interseptal thickening & traction bronchiectatic changes in both lungs which is more suggestive of NSIP.she was advised to take drugs regularly. CONCLUSIONS: AIH has multitude of extrahepatic manifestations but ILD has not been well delineated.Available case reports have suggested the possibility of coexistence of AIH and ILD. So in this case ILD can be an extrahepatic manifestation of AIH.She is on followup for other associated CTD’s. CLINICAL IMPLICATIONS: In systemic diseases like CTD dilemmas are still present in arriving causal & casual associations.High suspicion is needed in view of diagnostic and management in multi system involved conditions. DISCLOSURE: No significant relationships. KEYWORD: Autoimmune hepatitis,interstitial lung disease" @default.
- W3037065400 created "2020-07-02" @default.
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- W3037065400 date "2020-06-01" @default.
- W3037065400 modified "2023-09-27" @default.
- W3037065400 title "INTERSTITIAL LUNG DISEASE AS AN EXTRAHEPATIC MANIFESTATION OF AUTOIMMUNE HEPATITIS" @default.
- W3037065400 doi "https://doi.org/10.1016/j.chest.2020.05.406" @default.
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