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- W3037108448 abstract "In recent decades, while the incidence of thyroid cancer has increased exponentially around the world, mortality has remained stable. The vast majority of this increase is attributable to the identification of intrathyroidal papillary microcarcinomas, which exhibit slow growth rates with indolent courses. A diagnosis of thyroid cancer based upon the presence of these small tumors could be considered as an overdiagnosis, as the majority of these tumors would not likely result in death if left untreated. Although surgical resection was the classical standard therapy for papillary microcarcinomas, active surveillance (AS) has emerged over the last three decades as an alternative approach that is aimed to recognize a minority group of patients who will clinically progress and would likely benefit from rescue surgery. Despite the encouraging results of AS, its implementation in clinical practice is strongly influenced by psychosocial factors. The aim of this review is to describe the epidemiology, clinical evolution, prognostic factors, and mortality of papillary thyroid microcarcinomas. We also summarize the AS strategy according to published evidence, characterize the criteria for selecting patients for AS according to risk factors and environmental characteristics, as well as analyze the current limitations for AS implementation." @default.
- W3037108448 created "2020-07-02" @default.
- W3037108448 creator A5055373420 @default.
- W3037108448 creator A5067746841 @default.
- W3037108448 date "2020-06-24" @default.
- W3037108448 modified "2023-09-26" @default.
- W3037108448 title "Active surveillance in low risk papillary thyroid carcinoma" @default.
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- W3037108448 doi "https://doi.org/10.5306/wjco.v11.i6.320" @default.
- W3037108448 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7450818" @default.
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