Matches in SemOpenAlex for { <https://semopenalex.org/work/W3037168713> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W3037168713 abstract "Background/Aim: The current study aimed to evaluate the impact of sustained virological response (SVR) after two sofosbuvir (SOF) containing regimens on the clinical outcomes, non invasive markers of hepatic fibrosis and liver stiffness. Patients and Methods: The study included 200 patients with compensated HCV cirrhosis. Group 1: received SOF and Ribavirin (RBV) for 6 months, Group 2: received SOF, Daclatsvir (DAC) and RBV for 3 months. Hepatitis C Virus Ribonucleic Acid (HCV RNA) by Polymerase Chain Reaction (PCR) was done at baseline, end of treatment (EOT), SVR12, SVR48. Model for end stage liver disease (MELD) score was calculated, the aspartate aminotransferase to platelet ratio index (APRI) and Fibrosis-4 (FIB-4) scores were done. FibroScan was done at baseline and SVR48. Results: SVR12 occured in 75% and 96% in group 1 and 2, respectively. There was improvement in both of APRI and FIB-4 scores at EOT in the two groups, and maintained to SVR48. A significant improvement in mean liver stiffness (LS) occurred at SVR48 compared to baseline in the study groups. Improvement in LS was observed more in group 2. There was a significant decrease in the mean value of MELD score in group 2 and non-significant decrease in group 1 at SVR48 in comparison to pre-treatment mean value. Conclusion: SOF/DAC/RBV was effective treatment regimen in compensated liver cirrhosis. This regimen resulted in significant improvement in MELD score, and liver stiffness at SVR48." @default.
- W3037168713 created "2020-07-02" @default.
- W3037168713 creator A5004984680 @default.
- W3037168713 creator A5012456586 @default.
- W3037168713 creator A5026841785 @default.
- W3037168713 creator A5030096234 @default.
- W3037168713 creator A5032396346 @default.
- W3037168713 creator A5040659619 @default.
- W3037168713 creator A5072090658 @default.
- W3037168713 creator A5078557728 @default.
- W3037168713 date "2020-07-01" @default.
- W3037168713 modified "2023-10-17" @default.
- W3037168713 title "Two Sofosbuvir Containing Regimens in Egyptian Hepatitis C Related Compensated Liver Cirrhosis: Impact on Clinical Outcome and Liver Stiffness" @default.
- W3037168713 cites W2021199098 @default.
- W3037168713 cites W2045073898 @default.
- W3037168713 cites W2068705922 @default.
- W3037168713 cites W2135867669 @default.
- W3037168713 cites W2306227468 @default.
- W3037168713 cites W2586995441 @default.
- W3037168713 cites W2761789646 @default.
- W3037168713 cites W2782532009 @default.
- W3037168713 doi "https://doi.org/10.21608/ejhm.2020.97938" @default.
- W3037168713 hasPublicationYear "2020" @default.
- W3037168713 type Work @default.
- W3037168713 sameAs 3037168713 @default.
- W3037168713 citedByCount "0" @default.
- W3037168713 crossrefType "journal-article" @default.
- W3037168713 hasAuthorship W3037168713A5004984680 @default.
- W3037168713 hasAuthorship W3037168713A5012456586 @default.
- W3037168713 hasAuthorship W3037168713A5026841785 @default.
- W3037168713 hasAuthorship W3037168713A5030096234 @default.
- W3037168713 hasAuthorship W3037168713A5032396346 @default.
- W3037168713 hasAuthorship W3037168713A5040659619 @default.
- W3037168713 hasAuthorship W3037168713A5072090658 @default.
- W3037168713 hasAuthorship W3037168713A5078557728 @default.
- W3037168713 hasBestOaLocation W30371687131 @default.
- W3037168713 hasConcept C126322002 @default.
- W3037168713 hasConcept C203014093 @default.
- W3037168713 hasConcept C2522874641 @default.
- W3037168713 hasConcept C2776408679 @default.
- W3037168713 hasConcept C2776455275 @default.
- W3037168713 hasConcept C2777075537 @default.
- W3037168713 hasConcept C2777214474 @default.
- W3037168713 hasConcept C2778390639 @default.
- W3037168713 hasConcept C2780040827 @default.
- W3037168713 hasConcept C2781413609 @default.
- W3037168713 hasConcept C71924100 @default.
- W3037168713 hasConcept C90924648 @default.
- W3037168713 hasConceptScore W3037168713C126322002 @default.
- W3037168713 hasConceptScore W3037168713C203014093 @default.
- W3037168713 hasConceptScore W3037168713C2522874641 @default.
- W3037168713 hasConceptScore W3037168713C2776408679 @default.
- W3037168713 hasConceptScore W3037168713C2776455275 @default.
- W3037168713 hasConceptScore W3037168713C2777075537 @default.
- W3037168713 hasConceptScore W3037168713C2777214474 @default.
- W3037168713 hasConceptScore W3037168713C2778390639 @default.
- W3037168713 hasConceptScore W3037168713C2780040827 @default.
- W3037168713 hasConceptScore W3037168713C2781413609 @default.
- W3037168713 hasConceptScore W3037168713C71924100 @default.
- W3037168713 hasConceptScore W3037168713C90924648 @default.
- W3037168713 hasLocation W30371687131 @default.
- W3037168713 hasOpenAccess W3037168713 @default.
- W3037168713 hasPrimaryLocation W30371687131 @default.
- W3037168713 hasRelatedWork W10794003 @default.
- W3037168713 hasRelatedWork W14051095 @default.
- W3037168713 hasRelatedWork W15377590 @default.
- W3037168713 hasRelatedWork W17747543 @default.
- W3037168713 hasRelatedWork W18197631 @default.
- W3037168713 hasRelatedWork W18648799 @default.
- W3037168713 hasRelatedWork W18895069 @default.
- W3037168713 hasRelatedWork W19385909 @default.
- W3037168713 hasRelatedWork W6348797 @default.
- W3037168713 hasRelatedWork W9418999 @default.
- W3037168713 isParatext "false" @default.
- W3037168713 isRetracted "false" @default.
- W3037168713 magId "3037168713" @default.
- W3037168713 workType "article" @default.